Cancer Precursors
Epidemiology, Detection, and Prevention. Foreword by Joseph F. Fraumeni
(Sprache: Englisch)
The purpose of this book is to bring together in one place a discussion of the methodological issues associated with the study of precancerous conditions, as well as reviews of the contributions of descriptive, analytical, and molecular epidemiological...
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Klappentext zu „Cancer Precursors “
The purpose of this book is to bring together in one place a discussion of the methodological issues associated with the study of precancerous conditions, as well as reviews of the contributions of descriptive, analytical, and molecular epidemiological research to knowledge about cancer precursors at specific anatomical locations. Such a book is particularly timely, given that the last few years have seen enormous progress in terms of molecular epidemiological research on cancers and their precursors. This research has focused essentially on the early natural history of cancers, by helping to define the etiology of precursor lesions, improving the means of detecting them either directly or via testing of surrogate biomarkers, and by elucidating the role of remote c auses leading to the early onset of such lesions. Sections include the biological basic of carcinogenesis, the issues related to measurement and interpretation of cancer precursors (including intermediate endpoints andthe impact of measurement error in studying precursors), site-specific precancerous conditions including skin, lung, breast, cervix and prostate, as well as chapters on screening, chemoprevention and treatment. Cancer Precursors is a groundbreaking, multidisciplinary text for oncologists, epidemiologists, cancer researchers, pathologists, geneticists, molecular biologists, and graduate students in the cancer-related fields.
Inhaltsverzeichnis zu „Cancer Precursors “
From the contents:I. Biological Basis of Carcinogenesis
- II. Issues Related to Measurement and Interpretation of Cancer Precursors
- III. Site-Specific Precancerous Conditions
- IV. Control of Cancer Precursors
- V. Conclusion
Bibliographische Angaben
- 2002, 430 Seiten, Maße: 25,4 cm, Gebunden, Englisch
- Mitarbeit:Fraumeni, J. F.; Rohan, Thomas E.; Franco, Eduardo L.
- Verlag: Springer, New York
- ISBN-10: 0387951881
- ISBN-13: 9780387951881
Sprache:
Englisch
Rezension zu „Cancer Precursors “
From the reviews:"Drs. Franco and Rohan bring together a timely and comprehensive set of reviews describing the biologic basis of carcinogenesis, issues related to measurement and interpretation of cancer precursors, site specific precancerous conditions, and control of cancer precursors ...The book has several important strengths, most notably the wealth of current information on cancer precursors and related topics provided by an impressive cast of cancer researchers. ... it effectively provides specific and compelling reasons for studying cancer precursors, the most up-to-date and comprehensive collection of reviews on the topic, and a realistic picture of the complexities facing research of cancer precursors." -- American Journal of Epidemiology
"In this book, Drs. Franco and Rohan have succeeded in preparing a comprehensive, timely, and critical review of the substantial progress that has been made in our understanding of cancer precursors. They have enlisted experts in the field who have contributed authoritative chapters to a wide variety of cancers with emphasis on the etiology and natural history, including the role of environmental and heritable factor that provoke normal cells to undergo malignant transformation. Epidemiologic data are linked whenever possible to molecular as well as clasical cellular pathology, providing a fuller understanding of the casual events and mechanisms that initiate the carcinogenic process." -- From the Foreward by Joseph F. Fraumeni, Jr., M.D., M.S.; Director, Division of Cancer Epidemiology and Genetics; National Cancer Institute; National Institutes of Health; Rockville, MD
"This first edition text presents epidemiological data on the importance of precursor lesions at all the major anatomical sites. ... The strongest and most interesting section of the book is part three, which deals with precursor lesions at each of the important anatomical sites. ... The most interesting chapters were those that sought to
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integrate the epidemiology, pathology and molecular biology of the disease ... . Overall, I found this book made interesting reading and certainly some chapters would serve as an excellent reference text." (R Ward, Cancer Forum, Vol. 26 (3), 2002)
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