Diseases of the Liver and Biliary System in Children

Section 1: Structure, Function and Repair

1. Structure, Function and Repair
Ulrich Baumann, Rachel Brown, Alastair Millar, Bobbie Jones, Patrick McKiernan

Section 2: Investigating the Liver

2. The approach to the child with liver disease: Differential diagnosis and useful investigations
Deirdre Kelly

3. Interventional Radiology in the Diagnosis & Management of Liver Disease
Philip John

Section 3: Supporting the Family

4. The Effects on Mother and Child
Jane Hartley

Section 4: Neonatal Liver Disease

5. The Jaundiced Baby
Eve Roberts

6. The Acutely Ill Baby
Patrick McKiernan

Section 5: Acute Liver Disease

7. Infective disorders of the liver
Suzanne Davison, Elizabeth Boxall

8. Fulminant Hepatitis and Acute Liver Failure
Estella Alonso, Rob Squires, Peter Whitington

Section 6: Liver Disease in Older Children

9. Auto Immune Liver Disease
Giorgina Mieli-Vergani, Diego Vergani

10. Drug Induced Liver Disease
Karen Murray

11. Congenital and Structural Abnormalities of the Liver
Jaime Liou Wolfe, Kathleen Schwarz

12. Non-Alcoholic Steatosis
Eve Roberts

13. Hepatobiliary Disease in Cystic Fibrosis
Carla Colombo

Section 7: Metabolic Liver Disease

14. Metabolic Liver Disease in Older Children
Anne Green, Anupam Chakrapani

15. Disorders of Copper Metabolism
Stuart Tanner

Section 8: Management of Chronic Liver Disease

16. Complications and Management of Chronic Liver Disease
Ross Shepherd

Section 9: The Liver and other Organs

17. The Liver in Systemic Illness
Sue Beath

18. Skin Disorders in Liver Disease
Indra van Mourik, Michelle Thomson

19. Dental Care of Children with Liver Disease
Marie-Therese Hosey, Victoria Clark

Section 10: Surgical Management of Liver Disease

20. Surgical Disorders of the Liver and Bile Ducts
Alastair Millar

21. Primary Hepatic Tumours
Bruce Morland, Jean De Ville

Section 11: Transplantation

22. Liver Transplantation
Deirdre Kelly, A.

Dr Deirdre Kelly is a consultant pediatric hepatologist at the Liver Unit of Birmingham Children's Hospital and Reader in Paediatric Hepatology at the University of Birmingham.

She was born and brought up in Calcutta, India, in the post-Raj era while her father was working for Lipton's Tea. She spent her early childhood in India and went to boarding school in Dublin when she was 12 years old. She first decided to become a doctor at the age of 8 and despite much opposition from family and nuns at her convent school, persisted and went to Trinity College Dublin to study medicine in 1967.

She originally planned to be a General Practitioner but in her Senior House Officer days was encouraged to take an academic line and apply for General Medicine rotations and take the membership exams. She trained first in adult medicine, and then in gastroenterology and hepatology in Dublin with Professor Donald Weir who encouraged her to do an MD thesis on folate catabolism with Professor John Scott, a world authority on folate metabolism.

While in Dublin she had her two delightful sons while juggling research/academic medicine/clinical practice and discovered the joys of being a mother.

In 1982, she moved to London to work with Dame Sheila Sherlock at the Royal Free Hospital, where she became interested in pediatric hepatology. Dr Kelly retrained in pediatrics with Professor Otto Wolff at Great Ormond Street and Professor John Walker Smith at Queen Elizabeth Hospital, Hackney.

In 1987 she went to work as an Assistant Professor in Pediatric Gastroenterology and Hepatology at the University of Nebraska in Omaha US.

Dr Kelly used this time to learn about caring for children undergoing liver transplantation. Equipped with these new skills she returned to Birmingham in 1989 to set up a National Liver Unit to care for children with liver disease and undergoing liver transplantation.

The Unit has been very successful and is one of the busiest pediatric liver transplant