Molecular Mechanisms Influencing Aggressive Behaviours
(Sprache: Englisch)
This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding human aggression. Chapters focus on the major current...
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This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding human aggression. Chapters focus on the major current experimental issues in the study of aggression in humans and animals.
Klappentext zu „Molecular Mechanisms Influencing Aggressive Behaviours “
The experimental analysis of aggression has been of interest to scientists for a long time and there have been many interdisciplinary studies of aggression in both animals and humans. However, during the past five years or so, the application of new molecular genetic techniques has enabled us to explore mechanisms of aggression in ways that were not previously possible, yielding new information and insights.This book features leading scientists from a broad spectrum of disciplines describing and discussing recent data on aggression in laboratory animals. Particular emphasis is placed on possible implications for understanding human aggression. Chapters cover the major current experimental issues in the study of aggression in humans and animals: sex differences in aggression and related hormonal effects; specific genes for neurotransmitters, neuropeptides and nitric oxide; and finally aggression in primates, both human and animal. The discussions published here deal with the specific problems of interpretation at the molecular level and also with general issues relating to our understanding of human and animal aggression.
This important book provides a comprehensive account of our current understanding of the underlying biology of aggression in humans and animals. It should prove invaluable to researchers in various branches of both neuroscience and psychology.
This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding human aggression. Chapters focus on the major current experimental issues in the study of aggression in humans and animals. The extensive discussions deal with specific problems of interpretation at the molecular level, as well as general issues relating to our understanding of human and animal aggression.
Inhaltsverzeichnis zu „Molecular Mechanisms Influencing Aggressive Behaviours “
- Symposium on Genomics of autoimmunity, held at the Novartis Foundation, London, 22-24 June 2004.- Editors: Gregory Bock (Organizer) and Jamie Goode.
- This symposium is based on a proposal by Abul Abbas, David Halfer and John Rioux.
- Abbul Abbas Chair's introduction.
- Patterns of genetic variation in humans and mice (Mark Daly).
- Discussion.
- Haplotype tagging in pharmacogenetics (David B. Goldstein).
- Discussion.
- Multiple sclerosis: a haplotype association study (Simon J. Foote, Justin P. Rubio,Melanie Bahlo,Trevor J. Kilpatrick, Terence P. Speed, Jim Stankovich, Rachel Burfoot, Helmut Butzkueven, Laura Johnson, Chris Wilkinson, Bruce Taylor, Michele Sale, Ingrid A. F. van der Mei, Joanne L. Dickinson and Patricia Groom).
- Discussion.
- Mapping genes for asthma and psoriasis (Juha Kere).
- Discussion.
- Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse (Linda S. Wicker, Carolyn L.Moule, Heather Fraser, Carlos Penha-Goncalves, Dan Rainbow, Valerie E. S. Garner, Giselle Chamberlain, Kara Hunter, Sarah Howlett, Jan Clark, Andrea Gonzalez-Munoz, Anne Marie Cumiskey, PaulTiffen, Joanna Howson, Barry Healy, Luc J. Smink, Amanda Kingsnorth, Paul A. Lyons, Simon Gregory, Jane Rogers, John A.Todd and Laurence B. Peterson).
- Discussion.
- The importance of epistatic interactions in the development of autoimmunity (Srividya Subramanian and Edward K. Wakeland).
- Discussion.
- Mapping autoimmune disease genes in humans: lessons from IBD and SLE 94 (Timothy J. Vyse, Angela Richardson, Emily Walsh, Lisa Farwell, Mark J. Daly, Cox Terhorst and John D.Rioux).
- Discussion.
- A combined genetics and genomics approach to unravelling molecular pathways in coeliac disease (Cisca Wijmenga and Martin C.Wapenaar).
- Discussion.
- Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus (Timothy W. Behrens, Robert R. Graham, Chieko Kyogoku, Emily C. Baechler, Paula S. Ramos,
... mehr
Clarence Gillett, Jason Bauer, Ward A. Ortmann, Keli L. Hippen, Erik Peterson, Carl D. Langefeld, Kathy L. Moser, Patrick M. Gaffney and Peter K. Gregersen).
- Discussion.
- A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signaling (Vigo Heissmeyer, Fernando Macian, Rajat Varma, Sin-Hyeog Im, Francisco Garcia-Cozar, Heidi F.Horton, Michael C. Byrne, Stefan Feske, K. Venuprasad, Hua Gu,Yun-Cai Liu, Michael L. Dustin and Anjana Rao).
- Discussion.
- Genetic lesions in thymic T cell clonal deletion and thresholds for autoimmunity (Adrian Liston and Christopher C. Goodnow).
- Discussion.
- An autoimmune disease-associated CTLA4 splice variant lacking the B7 binding domain signals negatively in T cells (Lalitha Vijayakrishnan, Jacqueline M. Slavik, Zsolt Illes, Dan Rainbow, Laurence B.Peterson, Arlene S.Sharpe, Linda S.Wicker and VijayK.Kuchroo).
- Discussion.
- Large-scale screens for cDNAs with in vivo activity (Adrian Ting, Stefan Lichtenthaler, Ramnik Xavier, Soon-Young Na, Shahrooz Rabizadeh, Tara Holmes and Brian Seed).
- Discussion.
- Genomic mining of new genes and pathways in innate and adaptive
- immunity (Jenny Ting).
- Discussion.
- Index of contributors.
- Subject index.
- Discussion.
- A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signaling (Vigo Heissmeyer, Fernando Macian, Rajat Varma, Sin-Hyeog Im, Francisco Garcia-Cozar, Heidi F.Horton, Michael C. Byrne, Stefan Feske, K. Venuprasad, Hua Gu,Yun-Cai Liu, Michael L. Dustin and Anjana Rao).
- Discussion.
- Genetic lesions in thymic T cell clonal deletion and thresholds for autoimmunity (Adrian Liston and Christopher C. Goodnow).
- Discussion.
- An autoimmune disease-associated CTLA4 splice variant lacking the B7 binding domain signals negatively in T cells (Lalitha Vijayakrishnan, Jacqueline M. Slavik, Zsolt Illes, Dan Rainbow, Laurence B.Peterson, Arlene S.Sharpe, Linda S.Wicker and VijayK.Kuchroo).
- Discussion.
- Large-scale screens for cDNAs with in vivo activity (Adrian Ting, Stefan Lichtenthaler, Ramnik Xavier, Soon-Young Na, Shahrooz Rabizadeh, Tara Holmes and Brian Seed).
- Discussion.
- Genomic mining of new genes and pathways in innate and adaptive
- immunity (Jenny Ting).
- Discussion.
- Index of contributors.
- Subject index.
... weniger
Autoren-Porträt
The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.
Bibliographische Angaben
- 2005, 1. Auflage, 416 Seiten, Gebunden, Englisch
- Verlag: Wiley & Sons
- ISBN-10: 0470010681
- ISBN-13: 9780470010686
Sprache:
Englisch
Pressezitat
"This is an excellent review of the current state of neurobiological research on aggression should be essential reading for any scientist working in the field." ( Doody s Health Services )
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