Patch-Clamp Methods and Protocols

- Pharmacological Analysis of Recombinant NR1a/2A and NR1a/2B NMDAReceptors Using Whole-Cell Patch Clamp Method

- Memantine as an Example of A Fast, Voltage-Dependent, Open Channel N-Methyl-D-Aspartate (NMDA) Receptor Blocker

- Methods for Evaluation of Positive Allosteric Modulators of Glutamate AMPA Receptors

- Automated Voltage Clamp Technique

- Flip-The-Tip: Automated Patch Clamping Based on Glass Electrodes

- The Roboocyte: Automated Electrophysiology Based on Xenopus Oocytes

- Infrared Guided Laser Stimulation as A Tool for Elucidating the Synaptic Site of Expression of Long-Term Synaptic Plasticity

- Single-Cell RT-PCR, A Technique to Decipher the Electrical, Anatomical and Genetic Determinants of Neuronal Diversity

- Mechanosensitive Ion Channels Investigated Simultaneously by Scanning Probe Microscopy and Patch Clamp

- Synaptic Connectivity in Engineered Neuronal Networks

- Modeling of Action Potential Generation in NG108-15 Cells

- Whole-Cell Voltage-Clamp on Skeletal Muscle Fibers with the Silicone-Clamp Technique

- Determination of Channel Properties at the Unitary Level in Adult Mammalian Isolated Cardiomyocytes

- Electrophysiological Properties of Embryonic Stem Cells During Differentiation into Cardiomyocyte-Like Cell Types

- Hybrid Neuronal Network Studies Under Dynamic Clamp

- Cardiac Channelopathies Studied with the Dynamic Action Potential Clamp Technique

- Principles of Single-Channel Kinetic Analysis

- Use of Xenopus Oocytes to Measure Ionic Selectivity of Pore-Forming Peptides and Ion Channels

- Estimation of Quantal Parameters with Multiple-Probability Fluctuation Analysis

From the reviews:"This book will be helpful to researchers already working in the field of electrophysiology, but also those coming to this field from pharmacological, physiological, and biophysical areas." - Doody's Book Review Service"'Patch-clamp: Methods and Protocols' introduces some common patch-clamp applications. It is intended to assist scientists in identifying problems, which could be best addressed by this technique. The book provides the step-by-step procedures to perform the experiments that answer those questions. ... It will be a useful companion for moderately advanced users wishing to extend their skills." (Maria Drigelova, General Physiology and Biophysics, Vol. 27, April, 2008)