BetaSys / Systems Biology (PDF)
Systems Biology of Regulated Exocytosis in Pancreatic ß-Cells
(Sprache: Englisch)
The insulin secreting ß-cell is one of the most specialized cell types with diverse and multi-functional components (genes, gene products, organelles and metabolites) and a multitude of regulatory strategies in response to internal and environmental...
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The insulin secreting ß-cell is one of the most specialized cell types with diverse and multi-functional components (genes, gene products, organelles and metabolites) and a multitude of regulatory strategies in response to internal and environmental signals. This book looks at the technological advances that make simultaneous detection of thousands of biological variables possible; at a substantial variety of mathematical models and numerical simulations that aim to explain major aspects of the ß-cell function; and at the challenge to formulate a comprehensive and robust model of the main networks of the underlying biochemical and physical processes for diagnostic and therapeutic use.
Bibliographische Angaben
- Autoren: Bernhelm Booss-Bavnbek , Erik Renström , Beate Klösgen , Jesper Larsen
- 2011, 2011, 556 Seiten, Englisch
- Herausgegeben: Bernhelm Booß-Bavnbek, Beate Klösgen, Jesper Larsen, Flemming Pociot, Erik Renström
- Verlag: Springer-Verlag GmbH
- ISBN-10: 144196956X
- ISBN-13: 9781441969569
- Erscheinungsdatum: 02.03.2011
Abhängig von Bildschirmgröße und eingestellter Schriftgröße kann die Seitenzahl auf Ihrem Lesegerät variieren.
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- Dateiformat: PDF
- Größe: 13 MB
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Sprache:
Englisch
Pressezitat
From the reviews:“This second volume is Springer’s Systems Biology series focuses on the organisation of pancreatic insulin-producing beta cells, with a particular focus on the technological approaches deemed necessary to further our understanding of beta cell physiology and the pathogenesis of diabetes. … I warmly recommend should be on the shelves of all research laboratories involved in modern beta cell research.” (P. Meda, Diabetologia, Vol. 54, 2011)
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