Advances in Down Syndrome Research

- A new mouse model for Down syndrome

- Predicting pathway perturbations in Down syndrome

- Aberrant protein expression of transcription factors BACH1 and ERG, both encoded on chromosome 21, in brains of patients with Down syndrome and Alzheimer's disease

- Cell cycle and cell size regulation in Down Syndrome cells

- Transcription factor REST dependent proteins are comparable between Down Syndrome and control brains: challenging a hypothesis

- An altered antioxidant balance occurs in Down syndrome fetal organs: Implications for the "gene dosage effect" hypothesis

- Overexpression of Cl-tetrahydrofolate synthase in fetal Down Syndrome brain

- Increased expression of human reduced folate carrier in fetal Down syndrome brain

Ch.omosome 21 KIR channels in brain development

- Reduction of chromatin assembly factor 1 p60 and C21orf2 protein, encoded on chromosome 21, in Down Syndrome brain

- The MNB/DYRK1A protein kinase: Neurobiological functions and Down syndrome implications

- The MNB/DYRK1A protein kinase: Genetic and biochemical properties

- Cytoskeleton derangement in brain of patients with Down Syndrome, Alzheimer's disease and Pick's disease

- The cerebral cortex in Fetal Down Syndrome

- Polysomnography in transgenic hSOD1 mice as Down syndrome model

- Spectrum of cognitive, behavioural and emotional problems in children and young adults with Down syndrome

- Overexpression of transcription factor BACH1 in fetal Down Syndrome brain

- Down syndrome and associated congenital malformations

- RNA Microarray analysis of channels and transporters in normal and fetal Down Syndrome (trisomy 21) brain

- Heart type fatty acid binding protein (H-FABP) is decreased in brains of patients with Down syndrome and Alzheimer's disease

- Stem cell marker expression in human trisomy 21 amniotic fluid cells and trophoblasts