Apoptosis, Cell Signaling, and Human Diseases

Section I. Kinases and Phosphatases Significance of Protein Kinase A in Cancer Maria V. Nesterova and Y. S. Cho-Chung Protein Kinase C and Cancer Mary E. Reyland The Role of PI3K-Akt Signal Transduction in Virus Infection Samantha Cooray Cyclin-Dependent Kinase 5: A Target for Neuroprotection? Frank Gillardon Critical Roles of the Raf/MEK/ERK Pathway in Apoptosis and Drug Resistance James A. McCubrey, Fred E. Bertrand, Linda S. Steelman, Fumin Chang, David M. Terrian, and Richard A. Franklin MAP Kinases Signaling in Human Diseases Philippe Roux and J.Blenis Serine/Threonine Protein Phosphates in Apoptosis Gro Gausdal, Camilla Krakstad, Lars Herfindal, and Stein Ove Doskeland Urokinase/Urokinase Receptor-Mediated Signaling in Cancer Sreerama Shetty, and Steven Idell Section II. Molecular Basis of Cell Death Signaling Pathways That Protect the Heart Against Apoptosis Induced by Ischemia and Reperfusion Zheqing Cai and Gregg L. Semenza Cyclooxygenase-2 Gene Expression: Transcriptional and Posttranscriptional Controls in Intestinal Tumorigenesis Shrikant Anant and Sripathi M. Sureban Death Receptors: Mechanisms, Biology and Therapeutic Potential Sharmila Shankar and Rakesh Srivastava DNA Damage-Dependent Apoptosis Tomasz Skorski The Role of Proteasome in Apoptosis Peter Low Apoptosis Induction in T Lymphocytes by HIV Maria Saveria Gilardini Montani Inhibitors of Apoptosis Proteins and Caspases Jai Yu, John Silke and Paul G. Ekert Intracellular Pathways Involved in DNA-Damage and Repair to Neuronal Apoptosis Maurizio Memo The Biology of Caspases Tasman James Daish and Sharad Kumar