Basic and Clinical Toxicology of Organophosphorus Compounds

Chemistry and classification of OP compounds.- History of use and epidemiology of organophosphorus poisoning.- Acute toxicity of organophosphorus compounds.- Chronic toxicity of organophosphorus compounds.- Toxicity and novel biomarkers of OP exposure.- Clinical management of acute OP pesticide poisoning.- Clinical management of organophosphorus nerve agents' poisonings.- Occupational and environmental aspects of organophosphorus compounds.- Summary, discussion and conclusions.

Mahdi Balali-Mood attendedTehran University, where he was awarded a B.Sc. First-Class Honor in Chemistryin 1963 and then an M.D. in 1970. After his medical military service andtraining in internal medicine and clinical toxicology, he was appointed anassistant professor in clinical toxicology and became the head of his newlyestablished Poisoning Treatment Center (PTC) at Mashhad University in 1974. Hewas awarded a scholarship from the Ministry of Science of Iran and completedhis Ph.D. in clinical pharmacology and toxicologyat Edinburgh University Medical School (1978-1981). He continued at the schoolas a lecturer until 1982, when he decided to return to Mashhad to advance his establishedPTC. Dr. Balali-Mood was promoted to associateprofessor and then full professor of medicine and clinical toxicology at theMashhad University of Medical Sciences (MUMS) in 1984 and 1988, respectively. He has served as a clinical toxicology adviser to theInternational Programme on Chemical Safety (IPCS) and the World HealthOrganization from 1989 to the present. He has also been a member of the IPCSProgramme Advisory Committee since 2000. Dr. Balali-Mood was a founding memberand the first president of the Iranian Society of Toxicology and was twice electedpresident of Irantox between 1989 and 2001. Hehas been amember of the Iranian Academy of MedicalSciences since its establishment in 1990. Incollaboration with a group of internationally recognized medical toxicologists,he founded the Asia-Pacific Association of Medical Toxicology (in 1989) andserved as the organization's first vice president and then as its president for8 years (1994-2001). He was elected as a permanent member of the Academy ofSciences for the Developing World in 1997. He was also a member of theScientific Advisory Board of the Organization for the Prohibition of ChemicalWeapons from 2004 to 2011. Additionally, he is the co-founder of the Medical Toxicology Research Centre,Faculty of Medicine, Mashhad University of