Bile Acids in Hepatobiliary Disease

Preface. List of Contributors. 1. Introduction; T.C. Northfield. Section I: Cholestatic Liver Disease: Physiology, Pathogenesis and Epidemiology. 2. Cellular and Molecular Mechanisms of Bile Salt Transport in Health and Disease; J.L. Boyer. 3. Biochemical Aspects; J. Reichen. 4. Immunological Aspects; M.F. Bassendine. Section II: Bile Acid Therapy. 5. Optimum Dose of UDCA in Primary Biliary Cirrhosis (PBC); A. Verma. 6. Ursodeoxycholic Acid - An Immunomodulator in Primary Biliary Cirrhosis? A.G. Lim, et al. Section III: Clinical Trials. 7. Primary Biliary Cirrhosis: Long-Term Management with Ursodeoxycholic Acid; J. Heathcote. 8. Management of Patients with Primary Schlerosing Cholangitis; A. Stiehl. 9. Genetic Aspects; R. Thompson. 10. Congenital Defects in Bile Acid Synthesis Cause A Spectrum of Diseases Manifest as Severe Cholestasis, Neurological Disease, and Fat-Soluble Vitamin Malabsorption; K.D.R. Setchell. 11. Cystic Fibrosis of the Liver; C. Colombo. 12. Canalicular Secretion of Lysyl-fluorescein Bile Acids in 17beta-estradiol Glucuronide (17betaEG) Induced Cholestasis: Protective Effect of S-andenosyl-L-methionine (SAMe); P. Milkiewicz. Section IV: Alcoholic and Other Liver Diseases. 13. Ethanol Metabolism; T. Peters. 14. Alcohol Abuse and Abstinence; H. Ghodse. 15. Pathogenesis of Alchoholic Liver Disease; C.S. Lieber. 16. Clinical Aspects of Alcoholic Liver Disease; R. Williams. Section V: Bile Acid Therapy. 17. Effect on Liver Function; P. Hayes. 18. Fibrosis Markers and Ursodeoxycholic Acid; J.M.C. Stenner. 19. Urdodeoxycholic Acid for Treatment of Chronic Hepatitis C: An `Interferon Sparing' Effect; A. Lanzini. Section VI: Cholesterol Gallstone Disease. 20. Pathogenesis of Cholesterol Gallstone Disease: Role of the Liver; M.C. Carey. 21. Pathogenesis of Gallstones: Events in Bile; T. Gilat. 22. Role of the Gallbladder in the Pathogenesis of Gallstone Disease; R.P. Jazrawi, et al. 23. The Role of the Large Intestine in Cholesterol Gallstone Formation;