Bone and Osteoarthritis
(Sprache: Englisch)
The molecular and cellular approaches to the relationship of joint and bone problems distinguish this from other books on the topic. Advances in bone and joint biology enable practitioners to approach clinical problems more comprehensively. Emphasis on...
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Klappentext zu „Bone and Osteoarthritis “
The molecular and cellular approaches to the relationship of joint and bone problems distinguish this from other books on the topic. Advances in bone and joint biology enable practitioners to approach clinical problems more comprehensively. Emphasis on genetics and on newer viewpoints and approaches, exemplified by the possible effect of subchondral bone on osteoarthritis, gives a wider viewpoint to the reader and may enable novel approaches to solving a clinical problem.Inhaltsverzeichnis zu „Bone and Osteoarthritis “
- Overview chapter on the pathogenesis of OA- The role of bone in the development of OA
- Bone derived factors (cytokines and growth factors) and their influence on cartilage
- The role of the synovium in OA
- The cartilage-bone interface in OA/calcified cartilage zone
- Cartilage matrix destruction: MMPs and TIMPs
- Anabolic mediators of cartilage healing
- Role of chondrocyte hypertrophy in OA
- The genetics of OA
- Animal Models of OA
- Biomechanical Factors in OA
- Treatment: Novel Pharmaceuticals
Autoren-Porträt
Series Editors of Topics in Bone Biology are: Professors Felix Bronner, PhD - University of Connecticut Health Center, Farmington, CT, USA, and Dr Mary C. Farach-Carson, PhD - the Department of Biology, University of Delaware, Newark, DE, USA. In this fourth volume, the Series Editors are joined by a co-editor with special expertise in the volume topic, Dr Richard F. Loeser, MD, the Robert S. Katz, MD - Joan and Paul Rubschlager Presidential Professor of Osteoarthritis Research in the Department of Internal Medicine, Section of Rheumatology with a conjoint appointment in the Department of Biochemistry, Rush University, Chicago, IL, USA.
Bibliographische Angaben
- 2007, 218 Seiten, 60 Abbildungen, Maße: 18,3 x 26 cm, Gebunden, Englisch
- Herausgegeben: Mary C. Farach-Carson, Felix Bronner
- Verlag: Springer
- ISBN-10: 1846285135
- ISBN-13: 9781846285134
- Erscheinungsdatum: 07.11.2007
Sprache:
Englisch
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