Cancer Risk Evaluation

Preface Introduction MODELS AND APPROACHES Models of cancer development: genetic and environmental influences (Jandrig) Endogenous DNA damage and its relevance for the initiation of carcinogenesis (Epe, Fusser) The IARC Monographs Programme: cancer-hazard identification as a first step in cancer-risk assessment and cancer prevention (Baan, Cogliano) EPIDEMIOLOGICAL RESEARCH The role of epidemiology in cancer risk assessment of non-ionising radiation (Schüz, Berg-Beckhoff, Schlehofer, Blettner) The role of epidemiology in cancer risk assessment of ionizing radiation (Wakeford) ANIMAL STUDIES Animal studies on RF-EMF cancer effects (Dasenbrock, Buschmann) Animal studies in carcinogen identification: The example of power-frequency (50/60 Hz) magnetic fields (McCormick) GENOTOXICITY STUDIES Chromosomal aberrations in human populations and cancer (Obe, Lloyd, Durante) Cytogenetic studies in mammalian somatic cells exposed to radiofrequency radiation: A meta-analysis (Vijayalaxmi , Prihoda) OMICS - A NEW TOOL FOR CANCER RISK ASSESSMENT? Genomics and cancer risk assessment (Schweiger, Timmermann) Transcriptomics and cancer risk assessment (Kemmner) Proteomics and cancer risk assessment (Schramm) CURRENT USE OF OMICS STUDIES FOR CANCER RISK ASSESSMENT Omics in cancer risk assessment: Pathways to disease (Portier, Thomas) What have omics taught us about the health risks associated with exposure to low doses of ionizing radiation? (Morgan, Sowa) Current use of omics studies for cancer risk assessment: Transcriptomics approach in RF-EMF research (Mevissen) Proteomics approach In mobile phone radiation research (Leszczynski) CHALLENGES FOR RISK MANAGEMENT Evaluating the reliability of controversial scientific results (Lerchl) Comparative risk assessment with ionising and non-ionising radiations (Kiefer) Communicating about uncertainties in cancer risk assessment (Wiedemann, Schütz) The Precautionary Principle and radiofrequency exposure from mobile phones (Marchant)

Günter Obe was full Professor at the University of Duisburg-Essen since 1988, he retired in 2004. He obtained his academic degree (Dr. rer. nat.) from the Free University Berlin at 1967 and was associate Professor at this University since 1974. His field of research was cytogenetics such as in vitro induction of chromosomal aberrations, cytogenetic population monitoring of persons exposed to suspected mutagens, mechanisms of the origin of chromosomal aberrations. He authored more than 300 scientific publications.

Burkhard Jandrig got his academic degree in biochemistry at the University of Leipzig. From 1982 up to 1991 he was research associate/group leader at the Institute of Cancer Research Berlin and worked in the areas of chemical carcinogenesis and multidrug resistance. From 1992 up to 2009 he was research associate/group leader at the Max-Delbrück-Center for Molecular Medicine (MDC) in Berlin. His research activities were in the fields of molecular carcinogenesis, tumor genetics and tumor virology. Since 2006 he is working in the research group bioethics and science communication.

Gary Marchant is the Lincoln Professor of Emerging Technologies, Law and Ethics at the Sandra Day OŽConnor College of Law at Arizona State University. He is also a Professor of Life Sciences at ASU and Executive Director of the ASU center for the Study of Law, Science and Technology. Professor Marchant has a Ph.D. in Genetics from the University of British Columbia, a Masters of Public Policy degree from the Kennedy School of Government, and a law degree from Harvard. He teaches and researches in the subject areas of environmental law, risk assessment and risk management, genetics and the law, biotechnology law, food and drug law, legal aspects of nanotechnology, and law, sciences and technology.

Holger Schütz studied educational sciences, psychology and philosophy at Technical Universities of Braunschweig and Berlin. He is now working at the Institute of Neurosciences and

"Overall, the book provides an excellent account of various aspects of cancer and radiation risk assessment for a broad understanding of principles and effects for the betterment of human health." ( Indian J Med Res , 1 March 2013)