Cerebral Small Vessel Disease

Preface; Part I. Classification, Pathology and Basic Aspects: 1. Definition and classification of small vessel diseases Leonardo Pantoni; 2. Pathology of cerebral small vessel disease Jun Ogata, Hiromichi Yamanishi and Hatsue Ishibashi-Ueda; 3. Pathological aspects of the ischemic consequences of small vessel disease on brain parenchyma Margaret Esiri and Elisabet Englund; 4. Pathological aspects of the hemorrhagic consequences of small vessel diseases on the brain Johannes Attems and Kurt A. Jellinger; 5. Experimental animal models of cerebral small vessel disease Atticus H. Hainsworth and Hugh S. Markus; 6. Sporadic small vessels disease: pathogenic aspects Joanna M. Wardlaw and Leonardo Pantoni; 7. Pathogenic aspects of hereditary small vessel disease of the brain Anne Joutel; 8. Hereditary cerebral small vessel disease and role of genetic factors Christian Opherk and Martin Dichgans; 9. The link between large artery aging and cerebral small vessel disease Angelo Scuteri and Edward G. Lakatta; 10. The neurovascular unit and possible influences on cerebral small vessel disease Gregory J. del Zoppo, Yoshikane Izawa and Brian T. Hawkins; Part II. Neuroimaging and Laboratory Aspects: 11. Conventional brain imaging of white matter lesions Franz Fazekas, Christian Enzinger, Stefan Ropele and Reinhold Schmidt; 12. Conventional imaging of lacunar infarcts Eric Jouvent and Hugues Chabriat; 13. Imaging of hemorrhagic cerebral small vessel disease Jennifer Linn, Steven Greenberg and Anand Viswanathan; 14. Nonconventional MR techniques for imaging cerebral small vessel disease David Nyenhuis and Glenn T. Stebbins; 15. Cerebral hemodynamics in cerebral small vessel disease Hugh S. Markus, Charlotte L. Allan and Klaus P. Ebmeier; 16. Markers of endothelial dysfunction, oxidative stress and inflammation in cerebral small vessels disease Francesca Pescini and Rosanna Abbate; 17. Cerebral small vessel disease: cerebrospinal fluid aspects Anders Wallin and Maria Bjerke; Part III.

Leonardo Pantoni, MD, PhD is Staff Neurologist, Azienda Ospedaliero Universitaria Careggi, Florence, Italy. Philip B. Gorelick, MD, MPH is Professor of Translational Science and Molecular Medicine, Michigan State University College of Human Medicine, and Medical Director, Hauenstein Neuroscience Center, Mercy Health at Saint Mary's, Grand Rapids, Michigan, USA.