Drug Addiction

I. General Topics 1. Per Svenning, Angus C. Nairn and Paul Greengard DARPP-32 mediates the actions of multiple drugs of abuse 2. Young-Won Chin, Marcy J. Balunas, Hee Byung Chai, and A. Douglas Kinghorn Drug discovery from natural sources 3. Patricia H. Reggio Computational methods in drug design: Modeling G protein-coupled receptor monomers, dimers and oligomers 4. Joni L Rutter Symbiotic relationship of pharmacogenetics and drugs of abuse 5. Eric Peterson, S. Michael Owens, and Ralph L. Henry Monoclonal antibody form and function: Manufacturing the right antibodies for treating drug abuse 6. MJ Kuhar, JN Jaworski, GW Hubert, KB Philpot and G. Dominguez CART peptides play a role in drug abuse and potential therapeutic agents 7. Madhavan P.N. Nair, Jessica L. Reynolds, Supriya D. Mahajan, Stanley A.Schwartz, Ravikumar Aalinkeel, Bindukumar B. Don Sykes RNAi directed inhibition of DC-SIGN in dendritic cells. Prospects for HIV-1 therapy 8. Martin W. Adler, Ellen B. Geller, Xiaohong Chen, and Thomas J. Rogers Viewing chemokines as a third major system in the brain 9. Andrea Piserchio, Mark Spaller, and Dale F. Mierke Targeting the PDZ domains of molecular scaffolds of transmembrane ion channels 10. Lorise C. Gahring and Scott W. Rogers Neuronal nicotinic acetylcholine receptor expression and function on non-neuronal cells II. Transporters & stimulants & HALLUCINOGENS 1. Evan L. Riddle, Annette E. Fleckenstein and Glen R. Hanson Role of monamine transporters in mediating psychostimulant effects 2. F. Ivy Carroll, James L. Howard, Leonard L. Howell, Barbara S. Fox, and Michael J. Kuhar Development of the dopamine transporter selective RTI-336as a pharmacotherapy for cocaine abuse 3. Kellie J. White, Crystal C. Walline, and Eric L. Barker Serotonin transporters: Implications for antidepressant drug development 4. Tobin J. Dickerson and Kim D. Janda Recent advances for the treatment of cocaine abuse: Central nervous system immunopharmacotherapy 5.Thomas E. Prisinzano,

From the reviews:"This book grew out of a symposium entitled 'Frontiers in Science: Drug Addiction-From Basic Research to Therapies' held at the end of 2004. ... The book is composed of 44 chapters, all concerned with basic science research relevant to drug dependence. ... even for basic scientists this book is best approached as one where at most a few chapters may be of interest to any researcher ... in drug addiction." (Jason White, Drug And Alcohol Review, Vol. 28, July, 2009)