Genetics

1 Genetics: The Study of Biological Information 2 Mendel's Breakthrough: Patterns, Particles, and Principles of Heredity 3 Extensions to Mendel: Complexities in Relating Genotype to Phenotype 4 The Chromosome Theory of Inheritance 5 Linkage, Recombination, and the Mapping of Genes on Chromosomes 6 DNA: How the Molecule of Heredity Carries, Replicates, and Recombines Information 7 Anatomy and Function of a Gene: Dissection Through Mutation 8 Gene Expression: The Flow of Genetic Information from DNA to RNA to Protein 9 Deconstructing the Genome: DNA at High Resolution 10 Reconstructing the Genome Through Genetic and Molecular Analysis 11 The Direct Detection of Genotype Distinguishes Individual Genomes 12 Systems Biology and Proteomics 13 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA 14 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes 15 The Prokaryotic Chromosome: Genetic Analysis in Bacteria 16 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of Inheritance 17 Gene Regulation in Prokaryotes 18 Gene Regulation in Eukaryotes 19 Cell-Cycle Regulation and the Genetics of Cancer 20 Using Genetics to Study Development 21 The Genetic Analysis of Populations and How They Evolve 22 Evolution at the Molecular Level

Dr. Leland H. Hartwell received his Ph.D from MIT. He has held Assistant and Associate Professorships at the University of California before joining the faculty of the University of Washington, where he continues as a Full Professor. In 1996, Dr. Hartwell joined the Fred Hutchinson Cancer Research Center as a Full Member and Senior Advisor for Scientific Affairs, and was named President and Director of the Center in July, 1997. Dr. Hartwell has received numerous awards and honors in the course of his career. Among them he received the Brandeis university Rosenteil Award in 1993, and the sloan-kettering Cancer Center Katherine Berkan Judd Award as well as the Genetics Society of America Medal in 1994. In 1995 he was awarded the MGH Warren Triennial Price and in 1996 was awarded the Columbia University Horwitz Award and the Passano Award. Dr. Hartwell received the Albert Lasker Award for medical research in 1998.Dr. Michael Goldberg is a professor at Cornell University where he teaches introductory Genetics. He was an undergraduate at Yale University, and received his PhD in Biochemistry from Stanford University. Dr. Goldberg performed postdoctoral research at the Biozentrum of the University of Basel (Switzerland), posdoctoral research at the Biozentrum of the University of Basel and at Harvard University, and received an NIH Fogarty Senior International Fellowship for study at Imperial College (England) and at the University fo Rome (Italy). His current research utilizes the tools of Drosophila genetics to investigate the mechansims that ensure proper chromosome segregation during mitosis and meiosis.