Handbook of Biodegradable Polymers
Synthesis, Characterization and Applications
(Sprache: Englisch)
A comprehensive overview of the synthesis of biodegradable polymers, covering everything from synthesis, isolation, and degradation mechanisms while also introducing useful applications, such as drug delivery systems and regenerative medicine. An...
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Produktinformationen zu „Handbook of Biodegradable Polymers “
A comprehensive overview of the synthesis of biodegradable polymers, covering everything from synthesis, isolation, and degradation mechanisms while also introducing useful applications, such as drug delivery systems and regenerative medicine. An introductory section covers such fundamentals as basic chemical reactions during degradation, the complexity of biological environments and experimental methods for monitoring degradation processes.
The result is a reliable reference source for those wanting to learn more about this important class of polymer materials, as well as scientists in the field seeking a deeper insight.
The result is a reliable reference source for those wanting to learn more about this important class of polymer materials, as well as scientists in the field seeking a deeper insight.
Klappentext zu „Handbook of Biodegradable Polymers “
A comprehensive overview of biodegradable polymers, covering everything from synthesis, characterization, and degradation mechanisms while also introducing useful applications, such as drug delivery systems and biomaterial-based regenerative therapies. An introductory section deals with such fundamentals as basic chemical reactions during degradation, the complexity of biological environments and experimental methods for monitoring degradation processes.The result is a reliable reference source for those wanting to learn more about this important class of polymer materials, as well as scientists in the field seeking a deeper insight.
A comprehensive overview of biodegradable polymers, covering everything from synthesis, characterization, and degradation mechanisms while also introducing useful applications, such as drug delivery systems and biomaterial-based regenerative therapies. An introductory section deals with such fundamentals as basic chemical reactions during degradation, the complexity of biological environments and experimental methods for monitoring degradation processes.
The result is a reliable reference source for those wanting to learn more about this important class of polymer materials, as well as scientists in the fi eld seeking a deeper insight.
The result is a reliable reference source for those wanting to learn more about this important class of polymer materials, as well as scientists in the fi eld seeking a deeper insight.
Inhaltsverzeichnis zu „Handbook of Biodegradable Polymers “
PrefacePOLYESTERS
Historical Background
Preparative Methods
Physical Properties
Degradation Mechanisms
Beyond Classical Poly(Hydroxycarboxylic Acids)
BIOTECHNOLOGICALLY PRODUCED BIODEGRADABLE POLYESTERS
Introduction
History
Polyhydroxyalkanoates - Granules Morphology
Biosynthesis and Biodegradability of Poly(3-Hydroxybutyrate) and Other Polyhydroxyalkanoates
Extraction and Recovery
Physical, Mechanical, and Thermal Properties of Polyhydroxyalkanoates
Future Directions
POLYANHYDRIDES
Introduction
Types of Polyanhydride
Synthesis
Properties
In Vitro Degradation and Erosion of Polyanhydrides
In Vivo Degradation and Elimination of Polyanhydrides
Toxicological Aspects of Polyanhydrides
Fabrication of Delivery Systems
Production and World Market
Biomedical Applications
POLY(ORTHO ESTERS)
Introduction
poe II
poe IV
Solid Polymers
Gel-Like Materials
Polymers Based on an Alternate Diketene Acetal
Conclusions
BIODEGRADABLE POLYMERS CMPOSED OF NATURALLY OCCURRING ALPHA-AMINO ACIDS
Introduction
Amino Acid-Based Biodegradable Polymers AABBPs)
Conclusion and Perspectives
BIODEGRADABLE POLYURETHANES AND POLY(ESTER AMIDE)S
Chemistry and Properties of Biodegradable Polyurethanes
Biodegradation Mechanisms of Polyurethanes
New Polymerization Trends to Obtain Degradable Polyurethanes
Aliphatic Poly(ester amide)s: A Family of Biodegradable Thermoplastics with Interest as New Biomaterials
CARBOHYDRATES
Introduction
Alginate
Carrageenan
Cellulose and Its Derivatives
Microbial Cellulose
Chitin and Chitosan
Dextran
Gellan
Guar Gum
Hyaluronic Acid (Hyaluronan)
Puululan
Scleroglucan
Xanthan
Summary
BIODEGRADABLE SHAPE-MEMORY POLYMERS
Introduction
General Concept of SMPs
Classes of Degradable SMPs
Applications of Biodegradable SMPs
BIODEGRADABLE ELASTIC HYDROGELS FOR TISSUE EXPANDER APPLICATION
Introduction
Synthesis of Elastic Hydrogels
Physical Properties of Elastic Hydrogels
Applications of Elastic Hydrogels
Elastic
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Hydrogels for Tissue Expander Applications
BIODEGRADABLE DENDRIMERS AND DENDRITIC POLYMERS
Introduction
Challenges for Designing Biodegradable Dendrimers
Design of Self-Immolative Biodegradable Dendrimers
Biological Implications of Biodegradable Dendrimers
Future Perspectives of Biodegradable Dendrimers
Concluding Remarks
ANALYTICAL METHODS FOR MONITORING BIODEGRADATION PROCESSES OF ENVIRONMENTALLY DEGRADABLE POLYMERS
Introduction
Some Background
Defining Biodegradability
Mechanisms of Polymer Degradation
Measuring Biodegradation of Polymers
Conclusions
MODELING AND SIMULATION OF MICROBIAL DEPOLYMERIZATION PROCESSES OF XENOBIOTIC POLYMERS
Introduction
Analysis of Exogeneous Depolymerization
Materials and Methods
Analysis of Endogenous Depolymerization
Discussion
REGENERATIVE MEDICINE: RECONSTRUCTION OF TRACHEAL AND PHARYNGEAL MUCOSAL DEFECTS IN HEAD AND NECK SURGERY
Introduction
Regenerative Medicine for the Reconstruction of the Upper Aerodigestive Tract
Methods and Novel Therapeutical Options in Head and Neck Surgery
Vascularization of Tissue-Engineered Constructs
Application of Stem Cells in Regenerative Medicine
Conclusion
BIODEGRADABLE POLYMERS AS SCAFFOLDS FOR TISSUE ENGINEERING
Introduction
Short Overview of Regenerative Biology
Minimum Requirements for Tissue Engineering
Structure of Scaffolds
Biodegradable Polymers for Tissue Engineering
Some Examples for Clinical Application of Scaffold
Conclusions
DRUG DELIVERY SYSTEMS
Introduction
The Clinical Need for Drug Delivery Systems
Poly(Alpha-Hydroxyl Acids)
Polyanhydrides
Manufacturing Routes
Examples of Biodegradable Polymer Drug Delivery Systems Under Development
Concluding Remarks
OXO-BIODEGRADABLE POLYMERS: PRESENT STATUS AND FUTURE PERSPECTIVES
I
BIODEGRADABLE DENDRIMERS AND DENDRITIC POLYMERS
Introduction
Challenges for Designing Biodegradable Dendrimers
Design of Self-Immolative Biodegradable Dendrimers
Biological Implications of Biodegradable Dendrimers
Future Perspectives of Biodegradable Dendrimers
Concluding Remarks
ANALYTICAL METHODS FOR MONITORING BIODEGRADATION PROCESSES OF ENVIRONMENTALLY DEGRADABLE POLYMERS
Introduction
Some Background
Defining Biodegradability
Mechanisms of Polymer Degradation
Measuring Biodegradation of Polymers
Conclusions
MODELING AND SIMULATION OF MICROBIAL DEPOLYMERIZATION PROCESSES OF XENOBIOTIC POLYMERS
Introduction
Analysis of Exogeneous Depolymerization
Materials and Methods
Analysis of Endogenous Depolymerization
Discussion
REGENERATIVE MEDICINE: RECONSTRUCTION OF TRACHEAL AND PHARYNGEAL MUCOSAL DEFECTS IN HEAD AND NECK SURGERY
Introduction
Regenerative Medicine for the Reconstruction of the Upper Aerodigestive Tract
Methods and Novel Therapeutical Options in Head and Neck Surgery
Vascularization of Tissue-Engineered Constructs
Application of Stem Cells in Regenerative Medicine
Conclusion
BIODEGRADABLE POLYMERS AS SCAFFOLDS FOR TISSUE ENGINEERING
Introduction
Short Overview of Regenerative Biology
Minimum Requirements for Tissue Engineering
Structure of Scaffolds
Biodegradable Polymers for Tissue Engineering
Some Examples for Clinical Application of Scaffold
Conclusions
DRUG DELIVERY SYSTEMS
Introduction
The Clinical Need for Drug Delivery Systems
Poly(Alpha-Hydroxyl Acids)
Polyanhydrides
Manufacturing Routes
Examples of Biodegradable Polymer Drug Delivery Systems Under Development
Concluding Remarks
OXO-BIODEGRADABLE POLYMERS: PRESENT STATUS AND FUTURE PERSPECTIVES
I
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Autoren-Porträt von Andreas Lendlein
Professor Andreas Lendlein did his dissertation with Prof. Dr. Ulrich W. Suter at the material science department of the ETH in Zurich, Switzerland. In 1997 he moved, as a visiting scientist, to the group of Prof. Dr. Robert Langer at the Massachusetts Institute of Technology(MIT) in Cambridge, USA. He is director of the Institute of Polymer Research at the GKSS Research Center in Teltow (Germany). He is internationally known for his work on biomaterial research and development for application in regenerative medicine; he is also coordinator of the Helmholtz Programme Regenerative Medicine. He has received numerous grants and was laureate in the BioFuture Contest of the Ministry for Education and Research (BMBF), in 1999 he was honored by Pinguin Stiftung, in 2000 he received the Hermann-Schnell award of the GDCH, as well as the Innovationspreis of Zenit e. V.Michael Schroeter received his diploma and doctor's degree from the Technical University Berlin 1999 in Organic Chemistry. In 2000 he joined the GKSS Research Center with a post-doctoral position in material development for membrane separation. Since 2002 he works on the development on new stimuli-sensitive materials with Prof. Lendlein. From 2005 to 2007 he worked in a collaborative project at the Case Western Reserve University in Cleveland, Ohio (USA) as a Senior Research Associate with Prof. Christoph Weder in the synthesis of new types of conjugated polymers. Currently he holds the position of a junior group leader at GKSS since 2007. His primary research interests are design, synthesis and characterization of stimuli-sensitive, conjugated polymers for technical and medicinal applications.
Bibliographische Angaben
- Autor: Andreas Lendlein
- 2011, 1. Auflage, XX, 406 Seiten, 15 farbige Abbildungen, 152 Schwarz-Weiß-Abbildungen, Maße: 17,5 x 25 cm, Gebunden, Englisch
- Herausgegeben: Andreas Lendlein, Adam Sisson
- Verlag: Wiley-VCH
- ISBN-10: 3527324410
- ISBN-13: 9783527324415
- Erscheinungsdatum: 08.07.2011
Sprache:
Englisch
Pressezitat
"In short, the handbook is a very good reference for getting information about different types of biodegradable polymers with important examples, synthetic procedures, and application areas, specifically for medicine and biomedical applications." ( Materials Views , 15 July 2014)Kommentar zu "Handbook of Biodegradable Polymers"
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