Integrin-mediated Interactions between Cells and Biomimetic Materials
(Sprache: Englisch)
Based on the idea of self-assembled monolayers of alkanethiols on gold, it was the goal of this thesis to develop a versatile model system for an efficient and straightforward characterization of cell - biomaterial interactions on PEG-rich surfaces. The...
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Based on the idea of self-assembled monolayers of alkanethiols on gold, it was the goal of this thesis to develop a versatile model system for an efficient and straightforward characterization of cell - biomaterial interactions on PEG-rich surfaces. The necessary compounds for this model system should allow for mimicking the surface of polymeric poly(ethylene glycol)-rich biomaterials used for the design of cell carriers. By evaluating the adsorption of proteins and the adhesion characteristics of mammalian cells on these artificial surfaces, conclusions can be drawn, on how polymers should be engineered to achieve an optimal adhesion, growth or proliferation of cells. In particular, the consequences of an attachment of peptidic cell adhesion peptides and growth factors had to be elucidated.
Autoren-Porträt von Dr. Robert, Robert Knerr
Dr. Robert1996-2001 Studium der Pharmazie, Universität Regensburg2002 Approbation als Apotheker2002-2006 Promotion am Lehrstuhl für Pharmazeutische Technologie, Universität Regensburg, Prof. Dr. Achim Göpferich2005-2008: Leiter der Herstellung, AMAREG Pharma, RegensburgSeit 2008: Leiter der Pharmazeutischen Entwicklung, AMAREG Pharma, Regensburg
Bibliographische Angaben
- Autoren: Dr. Robert , Robert Knerr
- 2008, 232 Seiten, Maße: 15 x 22 cm, Kartoniert (TB), Englisch
- Verlag: VDM Verlag Dr. Müller e.K.
- ISBN-10: 363904200X
- ISBN-13: 9783639042009
Sprache:
Englisch
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