Macromolecular Drug Delivery

Macromolecular Drug Delivery Dr. Mattias Belting, ed. Table of ContentsPrefaceContributorsDevelopments in Macromolecular Drug Delivery; Review ChapterMattias Belting and Anders WittrupSynthetic vs. Natural/Biodegradable Polymers for Delivery of shRNA Based Cancer Therapies; Review chapterJohn S. Vorhies and John J. Nemunaitis siRNA and DNA Transfer to Cultured CellsBagavathi Gopalakrishnan and Jon WolffPoly(ß-amino esters): Procedures for Synthesis and Gene DeliveryJordan J. Green, Gregory T. Zugates, Robert Langer, and Daniel G. AndersonSystemic Delivery and Preclinical Evaluation of Nanoparticles Containing Antisense Oligonucleotides and siRNAsChuanbo Zhang, Joseph T. Newsome, Rajshree Mewani, Jin Pei, Prafulla C. Gokhale, and Usha N. KasidPeptide-based Delivery of Steric-block PNA OligonucleotidesSaïd Abes, Gabriela D. Ivanova, Rachida Abes, Andrey A. Arzumanov, Donna Williams, David Owen, Bernard Lebleu and Michael J. GaitCharacterizing Peptide Mediated DNA Internalization in Human Cancer CellsAnders Wittrup and Mattias BeltingSelection and Characterization of Antibodies from Phage Display Libraries against Internalizing Membrane AntigensJohan Fransson and Carl A. K. BorrebaeckArtificial Membrane Models for the Study of Macromolecular DeliveryLena Mäler and Astrid GräslundEnhanced Delivery of Macromolecules into Cells by ElectroendocytosisAlexander Barbul, Yulia Antov, Yosef Rosenberg and Rafi Korenstein In Vitro Systems for Studying Epithelial Transport of MacromoleculesNicole Daum, Andrea Neumeyer, BirgitWahl, Michael Bur, Claus-Michael LehrPreparation of Macromolecule-containing Dry Powders for Pulmonary DeliveryKelly S. Kraft and Marshall GrantMacromolecular Delivery Across the Blood-Brain BarrierKullervo HynynenPositron Emission Tomography (PET) and Macromolecular Delivery In Vivo Ludwig G. Strauss and Antonia Dimitrakopoulou-Strauss

From the reviews:"This volume ... provides details and discussions on contemporary methods available to address the limitations in the delivery of these agents. ... This comprehensive review will be of interest to scientists investigating either the in vitro or in vivo actions of macromolecule agents. Experts in biophysics, chemistry, cell biology, pharmaceutics, and/or preclinical and clinical dug discovery studies will find this book of value. Researchers involved in target therapy strategies for treatment of diseases will want a copy of this book." (Thomas L. Pazdernik, Doody's Review Service, 2009)"The title of the book will definitely attract readers of various backgrounds. It seems to indicate that the book covers the delivery of various kinds of macromolecular drugs. ... This will come as a surprise for experts working with other types of macromolecular therapeutics ... . the in vitro and in vivo models described in the book would be of interest to a broad scientific audience. ... the book definitely contains a lot of valuable information for experimental researchers." (Michal Pechar, ChemMedChem, Issue 4, 2009)