Mechanisms and Consequences of Proton Transport
(Sprache: Englisch)
"The principal focus of Mechanisms and Consequences of Proton Transport is on the gastric parietal cell and the acid secretory apparatus: how it operates and the consequences of malfunction.
Key topics include: - the fundamental structure and molecular...
Key topics include: - the fundamental structure and molecular...
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Klappentext zu „Mechanisms and Consequences of Proton Transport “
"The principal focus of Mechanisms and Consequences of Proton Transport is on the gastric parietal cell and the acid secretory apparatus: how it operates and the consequences of malfunction. Key topics include: - the fundamental structure and molecular operation of the gastric H+/K+ exchange pump;
- gene targeting studies directed at functional changes in the gastric epithelium and its ability to deal with the pathological consequences of acid and Helicobacter pylori infection; and
- regulation of parietal cell activation by protein kinases and ion transport pathways; the parietal cell as a model to study mechanisms for the translocation, docking, and fusion of membranes associated with regulated recruitment and recycling of transport proteins.This book provides cutting edge research for physiologists, cell biologists, and gastroenterologists who wish to understand the mechanisms of the gastric proton pump and the consequences of malfunction and pathology. "
Inhaltsverzeichnis zu „Mechanisms and Consequences of Proton Transport “
From the contents:- Preface
- Structure and Function of H,K-ATPASE - Molecular Basis for Drug Targets
- Gene Targeting Mouse; Mechanisms of Acid Secretion and Cell Proliferation
- Signal Transduction in the Parietal Cell; Pathway to Activation
- Cytoskeleton and Membrane Trafficking; The Gastric Parietal Cell as a Model
- Index
Autoren-Porträt
Tetsuro Urushidani is an associate professor in the Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, The University of Tokyo.John G. Forte is a professor in the Department of Molecular and Cell Biology, University of California at Berkeley.
George Sachs is Director of the Membrane Biology Laboratory, University of California, Los Angeles, Professor of Physiology and Medicine, UCLA, Wilshire Chair in Medicine, UCLA, and Co-Director of the Center for Ulcer Research and Education, UCLA.
Bibliographische Angaben
- 2002, 388 Seiten, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Tetsuro Urushidani, George Sachs, John G. Forte
- Verlag: Springer Netherlands
- ISBN-10: 1402070594
- ISBN-13: 9781402070594
- Erscheinungsdatum: 31.07.2002
Sprache:
Englisch
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