Mechanosensitivity and Mechanotransduction

Foreword by Holger Scholz; Editorial: Basic principles of mechanosensing and mechanotransduction in cells, Andre Kamkin and Irina Kiseleva; List of Contributors; Part I The Role of Cytoskeleton in Mechanosensitivity and Mechanotransduction: 1. Integrin-mediated mechanotransduction in vascular smooth muscle cells, Kay-Pong Yip, Lavanya Balasubramanian, James S. K. Sham; 2. The role of actin cytoskeleton in mechanosensation, Tianzhi Luo and Douglas N. Robinson; 3. Effect of Cytoskeleton on the Mechanosensitivity of Genes in Osteoblasts, Qiang Fu, Changjing Wu, Yourui Li, Yiping Zhang; 4. Involvement of the cytoskeletal elements in articular cartilage mechanotransduction, Emma J Blain; Part II Molecular Mechanisms of Mechanotransduction and Ion Channels Modifiers : 5. The role of nitric oxide in regulation of mechanically gated channels in the heart, Victor Kazanski, Andre Kamkin, Ekaterina Makarenko, Natalia Lysenko, Natalia Lapina, and Irina Kiseleva; 6. Role of signaling pathways in the myocardial response to biomechanical stress and in mechanotransduction in the heart, Danny Guo, Zamaneh Kassiri, and Gavin Y. Oudit; 7. Atomistic molecular simulation of gating modifier venom peptides - two binding modes and effects of lipid structure, Kazuhisa Nishizawa; Part III Mechanosensing and Mechanotransduction in Vascular Cells: 8. Cellular and molecular effects of mechanical stretch on vascular cells, Kou-Gi Shyu; 9. Role of Proteoglycans in Vascular Mechanotransduction, Aaron B. Baker; Part IV Mechanotransduction in the Lung: 10. Control of TRPV4 and its effect on the lung, James C. Parker and Mary I Townsley; 11. The Role of Protein-protein Interactions in Mechanotransduction: Implications in Ventilator Induced Lung Injury, Matt Rubacha and Mingyao Liu; Part V Mechanosensing and Mechanotransduction in Bone and Joint Tissues: 12. Cellular mechanisms of mechanotransduction in bone, Suzanne R.L. Young and Fredrick M. Pavalko; 13. The mechanosensitivity of cells in joint