Pharmaceutical Biotechnology

PART 1. INTRODUCTION TO CONCEPTS AND TECHNOLOGIES IN PHARMACEUTICAL BIOTECHNOLOGY
- A Primer on Pharmaceutical Biotechnology and Industrial Applications (Kayser, Müller)
- Procaryotic and Eucaryotic Cells in Biotech Production (Bechthold)
- Biopharmaceuticals Expressed in Plants (Knäblein)

PART 2. INDUSTRIAL DEVELOPMENT AND PRODUCTION PROCESS
- Scientific, Technical and Economic Aspects of Vaccine Research and Development (Gregersen)
- DNA Vaccines: From Research Tools in Mice to Vaccines in Humans (Ulmer)
- Characterisation and Bioanalytical Aspects of Recombinant Proteins as Pharmaceutical Drugs (Haunschild)
- Biogeneric Drugs (Hinderer)

PART 3. THERAPEUTIC PROTEINS
- SPECIAL PHARMACEUTICAL ASPECTS
- Pharmacokinetics and Pharmacodynamics of Biotech Drugs (Meibohm)
- Formulation of Biotech Drugs (Lipp)
- Patents in Biotechnology Industry: Legal and Ethical Issues (Resnick)
- Drug Approval in the EU und US (Walsh)

PART 4. BIOTECH 21
- INTO THE NEXT DECADE
- Rituximab (Grillo)
- Somatic Gene Therapy (Gottschalk)
- Non Viral Gene Delivery Systems (Kayser)
- Xenotransplantation in Pharmaceutical Biotechnology (Brunn)
- Sculpturing the Architecture of Mineralized Tissues: Tissue Engineering of Bone from Soluble Signals to Smart Biomimetic Matrices (Ripamonti)

INDEX

Oliver Kayser received his PhD at the Free University Berlin in 1997 following his fellowship at the University of Gainesville, Florida, whereupon he entered the pharmaceutical biotechnology industry. He is currently a lecturer at the Department of Pharmaceutics, Biopharmacy and Biotechnology at the FU Berlin, working on new biotech drugs from natural sources and on the development of drug delivery carriers based on nanosuspension and solid lipid nanoparticle enterprise technologies. Professor Rainer H. Müller is Head of the Department of Pharmaceutical Technology, Biotechnology & Quality Management at the Free University Berlin. His research focuses on solid lipid nanoparticles, nanosuspensions of poorly soluble drugs and drug targeting using the concept of "differential protein adsorption". He obtained his PhD at Kiel University in 1983, and spent 4 years as visiting scientist at the Pharmacy Department, University of Nottingham, UK and 1 year at the Université de Paris-Sud.