Principles and Practice of Biological Mass Spectrometry
(Sprache: Englisch)
Die Massenspektrometrie ist zweifellos eines der vielseitigsten Verfahren der analytischen Chemie. In erster Linie wird sie zur Bestimmung der Molekülmasse, Molekülstruktur, physikalischen Eigenschaften und quantitativen Zusammensetzung von Substanzen...
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Produktinformationen zu „Principles and Practice of Biological Mass Spectrometry “
Die Massenspektrometrie ist zweifellos eines der vielseitigsten Verfahren der analytischen Chemie. In erster Linie wird sie zur Bestimmung der Molekülmasse, Molekülstruktur, physikalischen Eigenschaften und quantitativen Zusammensetzung von Substanzen verwendet. Dieser Band behandelt neben den Grundprinzipien der Methode vor allem Anwendungen zur Untersuchung biologischer Stoffe, wobei der Schwerpunkt auf Proteinen und Peptiden liegt.
Klappentext zu „Principles and Practice of Biological Mass Spectrometry “
A practical introduction to contemporary instrumentation, techniques, and applicationsThis book provides professionals in the biological sciences with a solid basis in the fundamentals of contemporary mass spectrometry so that they can confidently choose and apply the best instrumentation and experimental approaches for their needs. The only single-volume guide of its kind, Principles and Practice of Biological Mass Spectrometry offers comprehensive coverage of the latest instrumentation, techniques, and applications in the rapidly expanding field of biological mass spectrometry, making it an excellent working resource for experts and novices alike.Principles and Practice of Biological Mass Spectrometry begins with a detailed review of the fundamentals of and recent developments in biological mass spectrometry instrumentation. This is followed by practical, well-illustrated instances of important mass spectrometric techniques, including: Tandem mass spectrometry Collision-induceddissociation Molecular mass determination Coupling of mass spectrometry with separation techniques QuantificationThe final portion of the book is devoted to an exploration of contemporary approachesto the characterization of the various classes of compounds relevant to the biological sciences. While the emphasis is on proteins and peptides, nucleic acid, carbohydrates, and lipids, pharmaceutical drugs and metabolites also receive extensive coverage. Throughout, coverage is generously supplemented with examples of applications across a wide range of commercial and academic venues.Principles and Practice of Biological Mass Spectrometry is an invaluable working resource for chemists, biochemists, biologists, molecular biologists, biomedical researchers, pharmacologists, immunologists, forensic scientists, environmental scientists, and all whose research involves the analysis of biological compounds.
Inhaltsverzeichnis zu „Principles and Practice of Biological Mass Spectrometry “
Introduction to Mass Spectrometry.Ionization Methods.
Mass Analysis and Ion Detection.
Tandem Mass Spectrometry.
Molecular Mass Measurement.
Quantitative Analysis.
Coupling of Separation Techniques with Mass Spectrometry.
Structural Analysis of Proteins.
Structural Characterization of Peptides.
Analysis of Glycoproteins and Oligosaccharides.
Folding-Unfolding and Higher-order Structures of Proteins.
Investigation of Noncovalent Interactions.
Structure Determination of Lipids and Glycolipids.
Screening Combinatorial Libraries.
Characterization of Oligonucleotides.
Applications to Real-World Problems.
Index.
Autoren-Porträt von Chhabil Dass
CHHABIL DASS, PhD, is an Associate Professor at the University of Memphis, Department of Chemistry.
Bibliographische Angaben
- Autor: Chhabil Dass
- 2000, 1. Auflage., XXX, 418 Seiten, Maße: 15,6 x 24 cm, Gebunden, Englisch
- Verlag: Wiley & Sons
- ISBN-10: 0471330531
- ISBN-13: 9780471330530
Sprache:
Englisch
Rezension zu „Principles and Practice of Biological Mass Spectrometry “
"Provides professionals...with fundamentals of contemporary mass spectrometry and gives advice...for different situations." (SciTech Book News, March 2001)"...the book is well-written...many up-to-date references are provided...reading it is worthwhile..." (Journal of the American Chemical Society, Vol. 123, No. 33, 2001)"...an excellent, self-contained book which is highly recommended..." (Spectroscopyeurope.com)
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