RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods
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Hidden Treasures in Contemporary RNA Sequencing
Serghei Mangul, Harry Taegyun Yang, Eleazar Eskin, Noah Zaitlen
53.49 €
192.59 €
64.99 €
Bioinformatics for Evolutionary Biologists
Bernhard Haubold, Angelika Börsch-Haubold
69.54 €
The existence of genes for RNA molecules not coding for proteins (ncRNAs) has been recognized since the 1950's, but until recently, aside from the critically important ribosomal and transfer RNA genes, most focus has been on protein coding genes. However, a long series of striking discoveries, from RNA's ability to carry out catalytic function, to discovery of riboswitches, microRNAs and other ribo-regulators performing critical tasks in essentially all living organisms, has created a burgeoning interest in this primordial component of the biosphere. However, the structural characteristics and evolutionary constraints on RNA molecules are very different from those of proteins, necessitating development of a completely new suite of informatic tools to address these challenges. In RNA Sequence, Structure, Function: Computational and Bioinformatic Methods, expert researchers in the field describe a substantial and relevant fraction of these methodologies from both practical and computational/algorithmic perspectives. Focusing on both of these directions addresses both the biologist interested in knowing more about RNA bioinformatics as well as the bioinformaticist interested in more detailed aspects of the algorithms. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results.
Thorough and intuitive, RNA Sequence, Structure, Function: Computational and Bioinformatic Methods aids scientists in continuing to study key methods and principles of RNA bioinformatics.
Jan Gorodkin, Ivo L. Hofacker and Walter L. Ruzzo
2. The Principles of RNA Structure Architecture
Christian Zwieb
3. The Determination of RNA Folding Nearest Neighbor Parameters
Mirela Andronescu, Anne Condon, Douglas H. Turner, and David H. Mathews
4. Energy Directed RNA Structure Prediction
Ivo L. Hofacker
5. Introduction to Stochastic Context Free Grammars
Robert Giegerich
6. An Introduction to RNA Databases
Marc P. Hoeppner, Lars E. Barquist, and Paul P. Gardner
7. Energy-based RNA Consensus Secondary Structure Prediction in Multiple Sequence
Alignments
Stefan Washietl and Stephan H. Bernhart and Manolis Kellis
8. SCFGs in RNA Secondary Structure Prediction: A Hands-on Approach
Zsuzsanna S¿uk¿osd, Ebbe S. Andersen and Rune Lyngsø
9. Annotating Functional RNAs in Genomes using Infernal
Eric P. Nawrocki
10. Class-specific Prediction of ncRNAs
Peter F. Stadler
11. Abstract Shape Analysis of RNA
Stefan Janssen and Robert Giegerich
12. Introduction to RNA Secondary Structure Comparison
Stefanie Schirmer, Yann Ponty, and Robert Giegerich
13. RNA Structural Alignments, Part I: Sankoff Based Approaches for Structural Alignments
Jakob Hull Havgaard and Jan Gorodkin
14. RNA Structural Alignments, Part II: Non-Sankoff Approaches for Structural Alignments
Kiyoshi Asai and Michiaki Hamada
15. De novo Discovery of Structured ncRNA Motifs in Genomic Sequences
Walter L. Ruzzo and Jan Gorodkin
16. Phylogeny and Evolution of RNA Structure
Tanja Gesell and Peter Schuster
17.
Ebbe Sloth Andersen
18. Automated Modeling of RNA 3D Structure
Kristian Rother, Magdalena Rother, Pawel Skiba, Janusz M. Bujnicki
19. Computational Prediction of RNA-RNA Interactions
Rolf Backofen
20. Computational Prediction of microRNA Genes
Jana Hertel, David Langenberger, and Peter F. Stadler
21. MicroRNA Target Finding by Comparative Genomics
Robin C. Friedman and Christopher B. Burge
22. Bioinformatics of siRNA Design
Hakim Tafer
23. RNA-protein Interactions: An Overview
Angela Re, Tejal Joshi, Eleonora Kulberkyte, Quaid Morris and Christopher T Workman
- 2014, 533 Seiten, 29 farbige Abbildungen, 101 Schwarz-Weiß-Abbildungen, Maße: 18,3 x 26 cm, Gebunden, Englisch
- Verlag: Humana Press
- ISBN-10: 162703708X
- ISBN-13: 9781627037082
- Erscheinungsdatum: 28.03.2014
Hidden Treasures in Contemporary RNA Sequencing
Serghei Mangul, Harry Taegyun Yang, Eleazar Eskin, Noah Zaitlen
53.49 €
192.59 €
64.99 €
Bioinformatics for Evolutionary Biologists
Bernhard Haubold, Angelika Börsch-Haubold
69.54 €
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