Stem Cell Therapy for Diabetes

Part I Beta-Cell Expansion and Regeneration

1. Pancreas and Islet Development George K. Gittes, Krishna Prasadan, and Sidhartha Tulachan

2. Islet and Pancreas Transplantation Davide Mineo, Gaetano Ciancio, George W. Burke, Rodolfo Alejandro, and Camillo Ricordi

3. Cell Cycle Regulation in Human Pancreatic Beta Cells Nathalie Fiaschi-Taesch, George Harb, Esra Karsiloglu, Karen K. Takane, and Andrew F. Stewart

4. Islet Regeneration Xiaobo Xu, Joke D'Hoker, Nico De Leu, Xiangwei Xiao, Yves Heremans, Mark Van De Casteele, and Harry Heimberg

5. Beta-Cell Expansion in Vitro Shimon Efrat

Part II Beta Cells from Non-beta Cells

6. What Does It Take to Make a Beta Cell? - Gordon C. Weir and Susan Bonner-Weir

7. Generation of Beta Cells from Acinar Cells Luc Baeyens, Ilse Rooman, and Luc Bouwens

8. Generation of Beta Cells from Pancreatic Duct Cells and/or Stem Cells Susan Bonner-Weir and Arun Sharma

9. Adult Cell Reprogramming: Using Nonpancreatic Cell Sources to Generate Surrogate Beta Cells for Treatment of Diabetes Irit Meivar-Levy, Vered Aviv, and Sarah Ferber

10. Embryonic Stem Cells as a Potential Cure for Diabetes Michael A. Bukys and Jan Jensen

Part III Tissue Engineering and Immune Protection

11. Functional Tissue Reconstruction with the Use of Biologic Scaffolds Stephen F. Badylak, Jennifer B. Ogilvie, and Thomas W. Gilbert

12. Immunoisolation in Cell Transplantation Riccardo Calafiore and Giuseppe Basta

13. Prevention of Islet Graft Rejection and Recipient Tolerization Eitan M. Akirav and Kevan C. Herold

Index- Gordon C. Weir and Susan Bonner-Weir

7. Generation of Beta Cells from Acinar Cells Luc Baeyens, Ilse Rooman, and Luc Bouwens

8. Generation of Beta Cells from Pancreatic Duct Cells and/or Stem Cell

From the reviews:

"From the same Series as the previous book, this volume reviews in 3 parts new methods in replacing beta cells to man. ... For research diabetologists." (Pediatric Endocrinology Reviews, Vol. 8 (2), December, 2010)

"This book details the promising role of stem cells to generate insulin-producing cells for replacement of diseased cells in diabetes therapy. ... All recent research findings are discussed, providing a well-rounded view of the current approaches to generating new insulin-producing cells. This book is informative, well illustrated with figures ... . I would suggest this book for scientists or clinicians who want to learn and understand new approaches to generate and restore beta cells as a promising approach to curing diabetes." (Damien Demozay, Doody's Review Service, July, 2010)

From the reviews:

"From the same Series as the previous book, this volume reviews in 3 parts new methods in replacing beta cells to man. ... For research diabetologists." (Pediatric Endocrinology Reviews, Vol. 8 (2), December, 2010)

"This book details the promising role of stem cells to generate insulin-producing cells for replacement of diseased cells in diabetes therapy. ... All recent research findings are discussed, providing a well-rounded view of the current approaches to generating new insulin-producing cells. This book is informative, well illustrated with figures ... . I would suggest this book for scientists or clinicians who want to learn and understand new approaches to generate and restore beta cells as a promising approach to curing diabetes." (Damien Demozay, Doody's Review Service, July, 2010)