The Glutamate Receptors

Preface Robert W. Gereau and Geoffrey T. Swanson AMPA Receptors Michael C. Ashby, Michael I. Daw, and John T. R. Isaac NMDA Receptors Ronald S. Petralia and Robert J. Wenthold Kainate Receptors Anis Contractor and Geoffrey T. Swanson Delta Receptors Michisuke Yuzaki Ionotropic Glutamate Receptors in Synaptic Plasticity Kenneth A. Pelkey and Chris J. McBain Structural Correlates of Ionotropic Glutamate Receptor Function Anders S. Kristensen, Kasper B. Hansen, Lonnie P. Wollmuth, Jan Egebjerg and Stephen F. Traynelis AMPA Receptors as Therapeutic Targets: Progress with Positive Receptor Modulators Gary Lynch and Christine M. Gall NMDA Receptors as Therapeutic Targets: Clinically Tolerated Strategies Huei-Sheng Vincent Chen, Dongxian Zhang and Stuart A. Lipton Structural features of metabotropic glutamate receptors David Hampson, Erin M. Rose, and Jordan E. Antflick Group I Metabotropic Glutamate Receptors (mGlu1 and mGlu5) Julie A. Saugstad, and Susan L. Ingram Group II Metabotropic Glutamate Receptors (mGlu2 and mGlu3) Michael P. Johnson and Darryle D. Schoepp Group III Metabotropic Glutamate Receptors (mGlu4, mGlu6, mGlu7 and mGlu8) Volker Neugebauer Metabotropic Glutamate Receptors in Synaptic Plasticity Stephen M. Fitzjohn and Zafar I. Bashir Metabotropic Glutamate Receptor Ligands in Therapeutics Ashley E. Brady and P. Jeffrey Conn

Glutamate receptors are critically important for normal brain function. The last decade has seen remarkable advances in our understanding of the physiological function and molecular structure of these proteins. This book provides a detailed review of the field, including a topical update to two excellent books, The Ionotropic Glutamate Receptors and The Metabotropic Glutamate Receptors. An exciting primer on glutamate receptors and their central role in neurotransmission, The Glutamate Receptors covers the extraordinary research and significant developments in the decade since the previous books were published. It also offers a snapshot of where prominent scientists expect to see research heading in the future. Both insightful and comprehensive, this book provides an invaluable reference for students and scientists on nearly every aspect of glutamate receptor structure and function.

From the reviews:"This is intended as a comprehensive primer for scientists and students studying the glutamate receptors. ... The book provides a good working knowledge of these receptors for all potential neuroscientist readers. ... it likely will best serve as a review for active researchers in the field of neuroscience. ... this book provides a timely update reflecting significant progress in the research in this field. ... an excellent resource for reviews on the neurobiology of individual receptor systems." (Kenneth E. McCarson, Doody's Review Service, June, 2007)