The Molecular Biology of Down Syndrome

- Molecular abnormalities of the brain in Down Syndrome: Relevance to Alzheimer's neurodegeneration
- Reduced aldehyde dehydrogenase levels in the brain of patients with Down Syndrome
- The Down Syndrome critical region
- Neuropathology
- C-fos expression in brains of patients with Down Syndrome
- Neuronal cell death in Down's Syndrome
- Altered gene expression in fetal Down Syndrome brain as revealed by the gene hunting technique of subtractive hybridization
- Gene expression in fetal Down Syndrome brain as revealed by subtractive hybridization
- Molecular misreading of genes in Down Syndrome as a model for the Alzheimer type of neurodegeneration
- Expression of the dihydropyrimidinase related protein 2 (DRP-2) in Down Syndrome and Alzheimer's disease brain is downregulated at the mRNA and dysregulated at the protein level
- Gene expression relevant to Down Syndrome: Problems and approaches
- Isolation and analysis of chromosome 21 genes potentially involved in Down Syndrome
- Differential display reveals deteriorated mRNA levels of NADH3 (complex I) in cerebellum of patients with Down Syndrome
- Serotonin (5-HT) in brains of adult patients with Down Syndrome
- Mechanisms of neuronal death in Downs Syndrome
- Impaired brain glucose metabolism in patients with Down Syndrome
- Oxidative stress and neural dysfunction in Down Syndrome
- Expression of the transcription factor ETS2 in brain of patients with Down Syndrome - Evidence against the overexpression-gene dosage hypothesis
- Neuronal apoplosis inhibitory protein (NAIP)-like immunoreactivity in brains of adult patients with Down Syndrome
- The "gene dosage effect" hypothesis versus the "amplified development instability" hypothesis in Down Syndrome
- Downregulation of the transcription factor scleraxis in brain of patients with Down Syndrome
- Heat-shock protein 70 levels in brain of patients with Down Syndrome and Alzheimers disease
- Increased levels of 14-3-3 gamma and epsilon proteins in