Theory and Mathematical Methods in Bioinformatics

- Outline

Part I: Mutations and alignments

- Introduction

- Stochastic models of mutations and structure analysis

- Modulus structure theory

- Super pairwise alignment

- Multiple sequence alignment

- Network structures of multiple sequences induced by mutation

- Alignment space

Part II: Protein configuration analysis

- Background information concerning the properties of proteins

- Informational and statistical iterative analysis of protein secondary structure prediction

3D structure analysis of the protein backbone and side chains

- Alignment of primary and 3D structures of proteins

- Depth analysis of protein spatial structure

- Analysis of the morphological features of protein spatial structure

- Semantic analysis for protein primary structure

Shiyi Shen

Since 1985, professor of mathematics, 1987-1998: chair of the department of mathematics, and the dean of the college of mathematical sciences; a standing committee of China Mathematical Society, the director of the Tianjin Mathematical Society. 1984-1986: visiting scholar of Cornell University; visiting scholar of Stanford University, and visiting researcher at the Hong Kong Chinese University. Shiyi Shen's fields of scientific interest are informatics and bioinformatics. His publications include about 60 journal papers and 6 books (Chinese).

Jack Tuszynski

Professor (from 07/1993 until present). Department of Physics, University of Alberta

Research Manager of the Neurons Group, (May 1, 2000- June 1, 2001) Starlab NV, Brussels, Belgium

Visiting Professor, Department of Physics, Ecole Normale Superieure, Lyon, France (December 2000, June-September 2001)

Senior Visiting Fellow, Laboratory of Biomolecular Dynamics, Catholic University of Leuven, Belgium (November-December 2000 and February-March 2001)

Adjunct Professor (from March 1, 2000). Department of Oncology, Division of Medical Physics, University of Alberta.

Visiting Professor (07/1995 - 09/1995). Institut fÿr Theoretische Physik, J. Liebig-Universitÿt GieÃYen, Germany.

Visiting Professor (07/1993 - 08/1994). Institut fÿr Theoretische Physik, H.Heine-Universitÿt Dÿsseldorf, Germany.

McCalla Professor (07/1992 - 07/1993). Department of Physics, University of Alberta.

Guest Professor (summer 1992), Visting Scientist (summer 1994, spring 1996). Institute of Mathematical Modelling, Danish Technical University, Lyngby.

Associate Professor (07/1990 - 07/1993). Department of Physics, University of Alberta, Edmonton. Tenure granted effective July 1, 1991.

Assistant Professor (01/1988 - 06/1990). Department of Physics, University of Alberta, Edmonton. Field: theoretical condensed