Total Intravenous Anesthesia and Target Controlled Infusions

PART 1.  INTRODUCTION/BACKGROUND.- 1. When and How Did It All Begin? A Brief History of Intravenous Anesthesia.- 2. The Development and Regulation of Commercial Devices for Target - Controlled Drug Infusion.- 3. The Memory Labyrinth: systems, processes and boundaries.- 4. Consciousness and Anaesthesia.- 5. Mechanisms of Intravenous Anaesthetic Action.- PART 2.  PRINCIPLES OF PHARMACOLOGICAL MODELING.- 6. Basic Pharmacology: Kinetics and Dynamics for Dummies.- 7. Pharmacokinetic-Pharmacodynamic Modelling of Anesthetic Drugs.- 8. Principles of Target Controlled Infusions.- 9.  Performance of Target-Controlled Infusion Systems.- 10. How to Select a PK/PD Model.- PART 3.  PHARMACOLOGY OF THE INTRAVENOUS ANESTHETIC AGENTS.- 11. Propofol PK-PD.- 12. Etomidate and Etomidate Analogues: Molecular Pharmacology and Behavioral Actions.- 13. Dexmedetomidine: The Science and Clinical Aspects in Adults and Children.- 14. Clinical Effects and Applications of Ketamine.- 15. Neuromuscular Blocking Drugs: Pharmacology, Physiology and Clinical Aspects.- 16. New and Upcoming Drugs: Intravenous Anesthetic Agents.- 17. Drug Interactions in Anesthesia.- PART 4. PRACTICAL CONDUCT OF SEDATION AND ANESTHESIA18. Pumps Pitfalls and Practicalities.- 19. EEG Monitoring of Depth of Anesthesia.- 20. Monitoring the analgesic component of anesthesia.- 21. Intravenous Drugs for Sedation: Target Controlled, Patient Controlled, and Patient Maintained Delivery.- 22. Pediatric TIVA/TCI: Case Presentations and Discussion.- 23. TCI/TIVA Adult Case Studies.- PART 5. SPECIAL POPULATIONS AND PROCEDURES.- 24. Intravenous Anesthesia in Obese Patients.- 25. Pharmacokinetics and Dynamics on the Pediatric Population.- 26. Clinical Pharmacology of Intravenous Sedation in Children.- 27. Sedation of the Critically Ill Child.- 28. TCI & TIVA for Neurosurgery: Considerations and Techniques.- 29. TCI in Special Patients Groups: The Elderly and Obese.- 30. TIVA for Cardiac Surgery.-31. TIVA/TCI in

Anthony R. Absalom, MBChB, FRCA, MD
Professor of Anesthesiology, The University Medical Center Groningen, University of Groningen, The NetherlandsDr. Absalom is internationally recognized as a leading expert on anaesthetic pharmacology and total intravenous anesthesia. He currently serves as Editor of the British Journal of Anaesthesia and is a former editorial board member of Trends in Anaesthesia and Critical Care. He is currently president of the Society for Intravenous Anesthesia (UK). In the past he has served as a board member of ISAP (International Society for Intravenous Anaesthesia) and as vice-president of the World Society of Intravenous Anaesthesia.
Keira P. Mason, MD is an Associate Professor of Anaesthesia (Radiology) at Harvard Medical School, , Boston Children's Hospital, Boston, MA. Dr. Mason is a Springer author. We recently published the expanded Second Edition of her critically and globally acclaimed book, Pediatric Sedation Outside of the Operating Room, 2nd ed, Mason, ed., (2015). During 1998-2014, Dr. Mason was Director of Radiology Anesthesia and Sedation at Boston Children's Hospital, where she developed a sedation and anesthesia program that continues to be nationally and internationally recognized. She is considered a pioneer of innovative and safe sedation protocols which have been adopted worldwide. Dr. Mason is past- Vice President of the World Society of Intravenous Anesthesia (Founding Board Member), and a frequent invited lecturer to national and international conferences, including Society of Interventional Radiology, American Society of Anesthesiologists, Radiological Society of North America, International Dental Congress on Anesthesia, Sedation, and Pain Control, Society of Ambulatory Anesthesia, Asian and Oceanic Society of Regional Anesthesia, Japanese Society for Intravenous Anesthesia, International Association of Pediatric Dentistry, All-African Anaesthesia Congress, Asian Society of Paediatric Anesthesiologists, and many

"Total Intravenous Anesthesia and Target Controlled Infusions is a traditional textbook that bills itself as a comprehensive guide to the subject. ... this textbook form part of the reference collection of all anesthetic department libraries. It is a high-quality volume, well bound with excellent color illustrations, printed on thick paper, and is a worthwhile purchase. ... Those that take the time to read a good portion of it will be richly rewarded in their increased understanding of TIVA." (Timothy G. Short and Gerard Willemsen, Anestesia & Analgesia, Vol. 125 (1), January, 2018)