UBE1C
(Sprache: Englisch)
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. NEDD8-activating enzyme E1 catalytic subunit is a protein that in humans is encoded by the UBA3 gene. The modification of...
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. NEDD8-activating enzyme E1 catalytic subunit is a protein that in humans is encoded by the UBA3 gene. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis.
Bibliographische Angaben
- 2010, 132 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Herausgegeben von Surhone, Lambert M.; Tennoe, Mariam T.; Henssonow, Susan F.
- Verlag: Betascript Publishing
- ISBN-10: 6131229333
- ISBN-13: 9786131229336
Sprache:
Englisch
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