Endolysosomal Cation Channels of the Transient Receptor Potential Superfamily (ePub)
Physiology, Pharmacology, and Mouse Models
(Sprache: Englisch)
Professorial Dissertation from the year 2014 in the subject Medicine - Pharmacology, Pharmacy, grade: Passed, LMU Munich (Pharmacy/Pharmacology), language: English, abstract: Lysosomes are cell organelles involved in the breakdown of proteins, lipids, and...
sofort als Download lieferbar
eBook (ePub)
18.99 €
- Lastschrift, Kreditkarte, Paypal, Rechnung
- Kostenloser tolino webreader
Produktdetails
Produktinformationen zu „Endolysosomal Cation Channels of the Transient Receptor Potential Superfamily (ePub)“
Professorial Dissertation from the year 2014 in the subject Medicine - Pharmacology, Pharmacy, grade: Passed, LMU Munich (Pharmacy/Pharmacology), language: English, abstract: Lysosomes are cell organelles involved in the breakdown of proteins, lipids, and other molecules and have been implicated not only in endolysosomal storage disorders (LSDs) such as mucolipidoses or mucopolysaccharidoses but also in metabolic diseases, neurodegenerative disorders such as Alzheimer's and Parkinson's disease, pigmentation disorders, or infectious diseases. Highly critical for the proper function of lysosomes, endosomes, and lysosome-related organelles is the tight regulation of various fusion and fission processes and the regulation of proton and other ionic concentrations within the endolysosomal system. Calcium permeable, non-selective cation channels of the TRP (transient receptor potential) superfamily, namely TRPML channels (mucolipins) and TPCs (two-pore channels) have been found to play important roles in these processes. This thesis provides insights into the function and physiology of TRPML and TPC channels, explains the molecular basis of pathologies associated with diseases caused by loss or mutation of these channels, and discusses potential therapeutic approaches.
Bibliographische Angaben
- Autor: Christian Grimm
- 2014, 1. Auflage, 44 Seiten, Englisch
- Verlag: GRIN Verlag
- ISBN-10: 3656849757
- ISBN-13: 9783656849759
- Erscheinungsdatum: 02.12.2014
Abhängig von Bildschirmgröße und eingestellter Schriftgröße kann die Seitenzahl auf Ihrem Lesegerät variieren.
eBook Informationen
- Dateiformat: ePub
- Größe: 4.79 MB
- Ohne Kopierschutz
- Vorlesefunktion
Sprache:
Englisch
Kommentar zu "Endolysosomal Cation Channels of the Transient Receptor Potential Superfamily"
0 Gebrauchte Artikel zu „Endolysosomal Cation Channels of the Transient Receptor Potential Superfamily“
Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
---|
Schreiben Sie einen Kommentar zu "Endolysosomal Cation Channels of the Transient Receptor Potential Superfamily".
Kommentar verfassen