Fundamentals of Heterocyclic Chemistry (PDF)

PREFACE. ACKNOWLEDGMENT. Chapter 1 THE SCOPE OF THE FIELD OF HETEROCYCLIC CHEMISTRY. References. Appendix. Chapter 2 COMMON RING SYSTEMS AND THE NAMING OF HETEROCYCLIC COMPOUNDS. 2.1. General. 2.2. Naming Simple Monocyclic Compounds. 2.3. Handling the "Extra Hydrogen". 2.4. Substituted Monocyclic Compounds. 2.5. Rings With More Than One Heteroatom. 2.6. Bicyclic Compounds. 2.7. Multicyclic Systems. 2.8. The Replacement Nomenclature System. 2.9. Saturated Bridged Ring Systems. References. Review Exercises. Chapter 3 NATURE AS A SOURCE OF HETEROCYCLIC COMPOUNDS. 3.1. General. 3.2. Naturally Occurring Nitrogen Heterocyclic Compounds. 3.3. Oxygen Compounds. 3.4. Sulfur and Phosphorus Heterocyclic Compounds in Nature. References. Chapter 4 PRINCIPLES OF SYNTHESIS OF AROMATIC HETEROCYCLES BY INTRAMOLECULAR CYCLIZATION. 4.1. General. 4.2. Some of the Classic Synthetic Methods. 4.3. Cyclizations Involving Metallic Complexes as Catalysts. 4.4. Cyclizations with Radical Intermediates. 4.5. Cyclizations by Intramolecular Wittig Reactions. 4.6. Synthesis of Heterocycles by the Alkene Metathesis Reaction. References. Review Exercises. Chapter 5 SYNTHESIS OF HETEROCYCLIC SYSTEMS BY CYCLOADDITION REACTIONS. 5.1. The Diels-Alder Reaction. 5.2. Dipolar Cycloadditions. 5.3. [2 + 2] Cycloadditions. References. Review Exercises. Chapter 6 AROMATICITY AND OTHER SPECIAL PROPERTIES OF HETEROCYCLES: PI-DEFICIENT RING SYSTEMS. 6.1. General. 6.2. Review of the Aromaticity of Benzene. 6.3. Pi-Deficient Aromatic Heterocycles. References. Review Exercises. Chapter 7 AROMATICITY AND OTHER SPECIAL PROPERTIES OF HETEROCYCLES: PI-EXCESSIVE RING SYSTEMS AND MESOIONIC RING SYSTEMS. 7.1. Pi-Excessive Aromatic Heterocycles. 7.2. Mesoionic Heterocycles. References. Review Exercises. Chapter 8 THE IMPORTANCE OF HETEROCYCLES IN MEDICINE. 8.1. General. 8.2. Historical. 8.3. Pyridines. 8.4. Indoles. 8.5. Quinolines. 8.6. Azepines. 8.7. Pyrimidines. 8.8. Concluding Remarks. References. Chapter 9 SYNTHETIC

LOUIS D. QUIN, PhD, is an Adjunct Professor at the
University of North Carolina Wilmington. Dr. Quin began his
academic career in 1956 with the Department of Chemistry at Duke
University, serving as department chairman from 1970 to 1976. After
retiring from Duke, he went to the University of Massachusetts
Amherst to head up its Chemistry Department, retiring in 1996. Dr.
Quin has written 250 research papers and written or co-edited eight
books on the subject of organophosphorus chemistry.

JOHN A. TYRELL, PhD, is Visiting Scientist in the
Department of Chemistry and Bio-chemistry at the University of
North Carolina Wilmington, where he teaches Fundamentals of
Heterocyclic Chemistry among other courses. Dr. Tyrell holds
sixty-eight patents and has more than twenty years of industrial
research experience, much of it focused on heterocyclic chemistry
research at Lederle Laboratories, General Electric Plastics, and
OxyChem.

Dieses eBook können Sie uneingeschränkt auf allen Geräten der tolino Familie lesen. Zum Lesen auf sonstigen eReadern und am PC benötigen Sie eine Adobe ID.