Proteomic Applications in Cancer Detection and Discovery (PDF)

Helps researchers in proteomics and oncology work together to
understand, prevent, and cure cancer

Proteomic data is increasingly important to understanding the
origin and progression of cancer; however, most oncologic
researchers who depend on proteomics for their studies do not
collect the data themselves. As a result, there is a knowledge gap
between scientists, who devise proteomic techniques and collect the
data, and the oncologic researchers, who are expected to interpret
and apply proteomic data. Bridging the gap between proteomics and
oncology research, this book explains how proteomic technology can
be used to address some of the most important questions in cancer
research.

Proteomic Applications in Cancer Detection and Discovery
enables readers to understand how proteomic data is acquired and
analyzed and how it is interpreted. Author Timothy Veenstra has
filled the book with examples--many based on his own firsthand
research experience--that clearly demonstrate the application
of proteomic technology in oncology research, including the
discovery of novel biomarkers for different types of cancers.

The book begins with a brief introduction to systems biology,
explaining why cancer is a systems biology disease. Next, it covers
such topics as:

* Mass spectrometry in cancer research

* Application of proteomics to global phosphorylation
analysis

* Search for biomarkers in biofluids

* Rise and fall of proteomic patterns for cancer diagnostics

* Emergence of protein arrays

* Role of proteomics in personalized medicine

The final chapter is dedicated to the future prospects of
proteomics in cancer research.

By guiding readers through the latest proteomic technologies and
their applications in cancer research, Proteomic Applications in
Cancer Detection and Discovery enhances the ability of
researchers in proteomics and researchers in oncology to
collaborate in order to better understand cancer and develop
strategies to prevent and treat it.