Proteostasis and Chaperone Surveillance (PDF)
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Proteostasis is central to the development of various human diseases caused due to excessive protein misfolding and the disregulation of the protein quality control system. In this book, respected researchers from many leading institutions contribute their insights on proteostasis maintenance. The coverage mainly focuses on the basics of maintaining proteostasis, the consequences of proteostatic system failure, and how chaperone systems constantly maintain proteostasis. In addition, the book presents in detail different treatment strategies for diseases caused by proteostatic system failure, as well as the inhibition of proteostatic failure using small molecule compounds. It examines advances in the modulation of proteopathies, providing a comprehensive source of key mechanistic insights on these diseases. As such, the book offers a valuable resource for beginners and more experienced investigators alike who are looking for detailed and reliable information on protein homeostasis, the diseases that can develop due to related imbalances, and the essential role of molecular and chemical chaperones.
Tanveer A. Dar is Assistant Professor in Clinical Biochemistry, University of Kashmir, Srinagar, Jammu and Kashmir, India. He received his Masters in Biochemistry from Hamdard University, New Delhi, India in 2003 and PhD in Biosciences from Jamia Millia Islamia, New Delhi in 2009. After completing his PhD, he joined Post-doctoral fellowship with Prof. Bruce E. Bowler in University of Montana, USA. His main research area is protein structural biology and medicinal plant proteomics. He has published more than 20 research papers in reputed international journals in the field of protein folding and their stability in presence of small molecules solutes. He is a recipient of the Junior Research Fellowship and Senior Research Fellowship by CSIR, New Delhi, India. He was
Dr. Parvaiz is Senior Assistant Professor in Department of Botany at Sri Pratap College, Srinagar, Jammu and Kashmir, India. He has completed his post graduation in Botany in 2000 from Jamia Hamdard, New Delhi, India. After receiving Doctorate degree from Indian Institute of Technology (IIT), Delhi, India, he joined International Centre for Genetic Engineering and Biotechnology, New Delhi in 2007. His main research area is Stress Physiology and Molecular Biology. He has published more than 40 research papers in peer-reviewed journals and 35 book chapters. He is also an Editor of 14 volumes (1 with Studium Press Pvt. India Ltd., New Delhi, India, 9 with Springer NY USA, 3 with Elsevier USA and 1 with John Wiley). He is a recipient of the Junior Research Fellowship and Senior Research Fellowship by CSIR, New Delhi, India. Dr. Parvaiz has been awarded the Young Scientist Award under Fast Track scheme in 2007 by the Department of Science and Technology (DST), Govt. of India. Dr. Parvaiz is actively engaged in studying the molecular and physio-biochemical response of different agricultural and horticultural plants under environmental stress.
- 2015, 1st ed. 2015, 180 Seiten, Englisch
- Herausgegeben: Laishram Rajendrakumar Singh, Tanveer Ali Dar, Parvaiz Ahmad
- Verlag: Springer-Verlag GmbH
- ISBN-10: 8132224671
- ISBN-13: 9788132224679
- Erscheinungsdatum: 26.11.2015
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