Reverse Genetics of RNA Viruses (PDF)

Reverse genetics, the genetic manipulation of RNA viruses to
create a wild-type or modified virus, has led to important advances
in our understanding of viral gene function and interaction with
host cells. Since many severe viral human and animal pathogens are
RNA viruses, including those responsible for polio, measles,
rotaviral diarrhoea and influenza infections, it is also an
extremely powerful technique with important potential application
for the prevention and control of a range of human and animal viral
diseases.

Reverse Genetics of RNA Viruses provides a comprehensive
account of the very latest developments in reverse genetics of RNA
viruses through a wide range of applications within each of the
core virus groups including; positive sense, negative sense and
double stranded RNA viruses. Written by a team of international
experts in the field, it provides a unique insight into how the
field has developed, what problems are being addressed now and
where applications may lead in the future. It will prove invaluable
to bioscience, medical and veterinary students, those starting
research in this area as well as other researchers and teachers
needing to update their knowledge of this fast-moving field.

* An authoritative, comprehensive overview of reverse genetics in
RNA Viruses.

* Includes numerous examples of cutting- edge applications of
reverse genetics within each of the RNA viral groups.

* Written by a team of international experts, including some of
the leading researchers in the field.