Role of Lipid Excipients in Modifying Oral and Parenteral Drug Delivery (PDF)
Basic Principles and Biological Examples
(Sprache: Englisch)
This comprehensive resource covers the fundamentals, formulation, and biopharmaceutical issues of lipid-based drug delivery. It presents the principles of lipid absorption and covers formulation issues, such as dissolution testing and stability testing, and...
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Produktinformationen zu „Role of Lipid Excipients in Modifying Oral and Parenteral Drug Delivery (PDF)“
This comprehensive resource covers the fundamentals, formulation, and biopharmaceutical issues of lipid-based drug delivery. It presents the principles of lipid absorption and covers formulation issues, such as dissolution testing and stability testing, and physiological and biopharmaceutical issues, including the role of specific enzymes, the evaluation of transport systems in the body, and the mechanisms governing the transport of water-insoluble drugs.
Inhaltsverzeichnis zu „Role of Lipid Excipients in Modifying Oral and Parenteral Drug Delivery (PDF)“
Preface. Contributors. Chapter 1. Interaction of Drug Transporters with Excipients (K. Sandy Pang, Lichuan Liu, and Huadong Sun). Chapter 2. Formulation Issues around Lipid-Based Oral and Parenteral Delivery Systems (Seong Hoon Jeong, Jae Hyung Park and Kinam Park). Chapter 3. Lipid-Based Parenteral Drug Delivery Systems: Biological Implications (Vladimir P. Torchilin). Chapter 4. Principles in the Development of Intravenous Lipid Emulsions (Joanna Rossi and Jean-Christophe Leroux). Chapter 5. Protein adsorption patterns on parenteral lipid formulations-key factor determining the in vivo fate (Rainer H. Muller and Torsten M. Goppert). Chapter 6. Nanoparticle targeting for drug delivery across the blood brain barrier (James Egbert, Werner Geldenhuys, Fancy Thomas, Paul R. Lockman, Russell J. Mumper and David D. Allen). Chapter 7. Lipid-Coated Perfluorocarbon Nanostructures as Parenteral Therapeutic Agents (Evan C. Unger, Terry O. Matsunaga and Reena Zutshi). Index.
Autoren-Porträt
KISHOR M. WASAN, PhD, is a Professor and DistinguishedUniversity Scholar at The University of British Columbia Faculty of
Pharmaceutical Sciences. He is the Chairman of the AAPS Focus Group
in Parenteral Lipid-Based Drug Delivery Systems. His research has
earned him over $10 million in grants and funding, and he has
written over 290 peer-reviewed publications and abstracts. In
addition, he holds five patents and has worked as a consultant and
publications reviewer. Dr. Wasan is a Fellow of the American
Association of Pharmaceutical Sciences (AAPS) and a member of the
Canadian Society of Pharmaceutical Sciences, American Pharmacists
Association (APhA), and Pharmaceutics and Drug Delivery Awards
Committee, among others.
Bibliographische Angaben
- 2006, 1. Auflage, 216 Seiten, Englisch
- Herausgegeben: Kishor M. Wasan
- Verlag: John Wiley & Sons
- ISBN-10: 0470097973
- ISBN-13: 9780470097977
- Erscheinungsdatum: 20.11.2006
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- Größe: 3.53 MB
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Englisch
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