Solid-Phase Organic Synthesis (PDF)
(Sprache: Englisch)
Solid-Phase Organic Synthesis Edited by Kevin Burgess, Texas A & M University Efficient, high-throughput chemistry is now the focus of many research laboratories. Solid-phase organic syntheses are central to many of these combinatorial and parallel...
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Solid-Phase Organic Synthesis Edited by Kevin Burgess, Texas A & M University Efficient, high-throughput chemistry is now the focus of many research laboratories. Solid-phase organic syntheses are central to many of these combinatorial and parallel screening methodologies. Consequently, they have been a major scientific theme of the 1990s and promise to remain prominent for the first part of the new millennium. Indeed, a bewildering number of papers have entered the literature on this topic; some report minor modifications enabling transformation of solution-phase methods to a solid support, while others report major innovations. Solid-Phase Organic Synthesis collects, highlights, and critiques some of the key developments in the field. Leading practitioners explain different perspectives on diverse aspects of the area. Specific topics covered include:
* Syntheses of guanidines
* Palladium-catalyzed C-C bond forming reactions
* S_nAr reactions for the formation of heterocycles
* Sequence-specific arylalkyne oligomers
* Resin-supported capture agents and other reagents
* Synthesis on pins
* Monitoring of supported reactions using IR
* Solid-phase syntheses of natural product derivatives
Of related interest . Combinatorial Chemistry and Molecular Diversity in Drug Discovery Eric M. Gordon and James F. Kerwin 1998 (0-471-15518-7) 544 pp. Combinatorial Chemistry Synthesis and Application Stephen R. Wilson and Anthony W. Czarnik 1997 (0-471-12687-X) 288 pp.
* Syntheses of guanidines
* Palladium-catalyzed C-C bond forming reactions
* S_nAr reactions for the formation of heterocycles
* Sequence-specific arylalkyne oligomers
* Resin-supported capture agents and other reagents
* Synthesis on pins
* Monitoring of supported reactions using IR
* Solid-phase syntheses of natural product derivatives
Of related interest . Combinatorial Chemistry and Molecular Diversity in Drug Discovery Eric M. Gordon and James F. Kerwin 1998 (0-471-15518-7) 544 pp. Combinatorial Chemistry Synthesis and Application Stephen R. Wilson and Anthony W. Czarnik 1997 (0-471-12687-X) 288 pp.
Inhaltsverzeichnis zu „Solid-Phase Organic Synthesis (PDF)“
Solid Phase Syntheses of Guanidines (K. Burgess & J. Chen). Palladium-catalyzed Carbon-carbon Bond Formation on Solid Supports (M. Todd & C. Abell). Benzofused Heterocycles via Solid-phase S_NAr Reactions (M. Schwarz & M. Gallop). Solid-phase Synthesis of Sequence-specific Phenylacetylene Oligomers (J. Moore, et al.). Polymer-assisted Solution Phase Methods for Chemical Library Synthesis (D. Flynn, et al.). Solid-phase Organic Synthesis on Radiation-grafted Polymer Surfaces: Application of SynPhase(TM) Crowns to Multiple Parallel Syntheses (I. James, et al.). Vibrational Spectroscopy for Optimization of Solid-phase Organic Syntheses (B. Yan). Recent Advances in Solid-phase Synthesis of Natural Products (L. Wilson).
Autoren-Porträt von Kevin Burgess
Kevin Burgess FRSC is a British chemist who has been Rachal Professor of Chemistry at Texas A&M University since 2004. He was educated at the University of Bath, the University of East Anglia and Darwin College, Cambridge.
Bibliographische Angaben
- Autor: Kevin Burgess
- 2004, 1. Auflage, 296 Seiten, Englisch
- Verlag: John Wiley & Sons
- ISBN-10: 0471458457
- ISBN-13: 9780471458456
- Erscheinungsdatum: 22.03.2004
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