Steroid Dimers (PDF)

Steroid dimers are an important group of compounds produced by
various marine organisms, and also synthesized in the laboratories.
This group of compounds possesses various pharmacological and
biological properties, and can also be used to create
"molecular umbrellas" for drug delivery.

Steroid Dimers: Chemistry and Applications in Drug Design and
Delivery provides an up-to-date overview on the chemistry and
applications of steroid dimers of natural and synthetic origins.
The book includes easy-to-follow synthetic protocols for various
classes of important dimeric steroids, source details, valuable
spectroscopic data and depiction of unique structural features of
natural steroidal dimers, and the Structure-Activity-Relationships
(SARs) of some pharmacologically active dimeric steroids. Topics
covered include:

* introduction to steroid dimers

* synthesis and chemistry of noncyclic and cyclic steroid
dimers

* naturally occurring steroid dimers - cephalostatins,
ritterazines and crellastatins

* biological and pharmacological functions of steroid dimers and
their application in drug design and discovery

* steroid dimers as "molecular umbrellas" for drug
delivery

Steroid Dimers: Chemistry and Applications in Drug Design and
Delivery is an essential guide to this important class of
natural and synthetic compounds for researchers and students of
natural products chemistry and biochemistry, synthetic organic
and medicinal chemistry, and drug design, discovery and
delivery.