Batch Effects and Noise in Microarray Experiments / Wiley Series in Probability and Statistics (PDF)
Sources and Solutions
(Sprache: Englisch)
Batch Effects and Noise in Microarray Experiments: Sources and
Solutions looks at the issue of technical noise and batch
effects in microarray studies and illustrates how to alleviate such
factors whilst interpreting the relevant biological...
Solutions looks at the issue of technical noise and batch
effects in microarray studies and illustrates how to alleviate such
factors whilst interpreting the relevant biological...
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Batch Effects and Noise in Microarray Experiments: Sources and
Solutions looks at the issue of technical noise and batch
effects in microarray studies and illustrates how to alleviate such
factors whilst interpreting the relevant biological information.
Each chapter focuses on sources of noise and batch effects
before starting an experiment, with examples of statistical methods
for detecting, measuring, and managing batch effects within and
across datasets provided online. Throughout the book the importance
of standardization and the value of standard operating procedures
in the development of genomics biomarkers is emphasized.
Key Features:
* A thorough introduction to Batch Effects and Noise in
Microrarray Experiments.
* A unique compilation of review and research articles on
handling of batch effects and technical and biological noise in
microarray data.
* An extensive overview of current standardization
initiatives.
* All datasets and methods used in the chapters, as well as
colour images, are available on href="http://www.the-batch-effect-book.org/">www.the-batch-effect-book.org,
so that the data can be reproduced.
An exciting compilation of state-of-the-art review chapters and
latest research results, which will benefit all those involved in
the planning, execution, and analysis of gene expression
studies.
Solutions looks at the issue of technical noise and batch
effects in microarray studies and illustrates how to alleviate such
factors whilst interpreting the relevant biological information.
Each chapter focuses on sources of noise and batch effects
before starting an experiment, with examples of statistical methods
for detecting, measuring, and managing batch effects within and
across datasets provided online. Throughout the book the importance
of standardization and the value of standard operating procedures
in the development of genomics biomarkers is emphasized.
Key Features:
* A thorough introduction to Batch Effects and Noise in
Microrarray Experiments.
* A unique compilation of review and research articles on
handling of batch effects and technical and biological noise in
microarray data.
* An extensive overview of current standardization
initiatives.
* All datasets and methods used in the chapters, as well as
colour images, are available on href="http://www.the-batch-effect-book.org/">www.the-batch-effect-book.org,
so that the data can be reproduced.
An exciting compilation of state-of-the-art review chapters and
latest research results, which will benefit all those involved in
the planning, execution, and analysis of gene expression
studies.
Autoren-Porträt von Andreas Scherer
Andreas Scherer studied biology in Cologne, Germany, andFreiburg, Germany, and received his Ph.D. for his studies in the
fields of genetics, developmental biology, and microbiology.
Following a postdoctoral position at UT Southwestern Medical Center
in Dallas, TX, he worked for many years in pharmaceutical industry
in various positions in the field of experimental and statistical
genomics biomarker discovery. In 2007, Andreas Scherer founded
Spheromics, a company specialized in analytical and consultancy
services in gene expression technologies and biomarker
development.
Bibliographische Angaben
- Autor: Andreas Scherer
- 2009, 1. Auflage, 272 Seiten, Englisch
- Verlag: John Wiley & Sons
- ISBN-10: 0470685999
- ISBN-13: 9780470685990
- Erscheinungsdatum: 13.10.2009
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- Größe: 4.95 MB
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Sprache:
Englisch
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