Arterial Mesenchyme and Arteriosclerosis

Section I The Problem in Perspective.- Mesenchymal Involvement in Arteriosclerosis.- Morphology of Mesenchymal Elements of Normal Artery, Fatty Streaks, and Plaques.- Reaction Patterns of Intimal Mesenchyme to Injury, and Repair in Atherosclerosis.- Proliferation of Arterial Cells in Atherosclerosis.- Section II Lipid-Connective Tissue Interactions.- The Macromolecules of the Intercellular Matrix of the Arterial Wall: Collagen, Elastin, Proteoglycans, and Glycoproteins.- Acid Glycosaminoglycan, Collagen and Elastin Content of Normal Artery, Fatty Streaks and Plaques.- Mucopolysaccharide-Lipoprotein Complexes in Atherosclerotic Aorta.- Some Aspects of the Organization and Interaction of Connective Tissue Proteoglycans.- Age Related and Atherosclerotic Changes in Aortic Elastin.- Components of the Protein-Lipid Complex of Arterial Elastin: Their Role in the Retention of Lipid in Atherosclerotic Lesions.- Studies on the Conformation and Interactions of Elastin.- Section III Tissue Culture Application in Connective Tissue Research.- Tissue Culture Technology Applicable to Arterial Mesenchyme.- Studies of Primate Arterial Smooth Muscle Cells in Relation to Atherosclerosis.- Production of Mucopolysaccharides, Collagen and Elastin Tissue by Aortic Medial Explants.- Effects of Serum Lipoproteins on the Morphology, Growth, and Metabolism of Arterial Smooth Muscle Cells.- Section IV Pathologic Processes and Connective Tissue Interactions.- Thrombosis and Connective Tissue Interrelationships in Arteriosclerosis.- Immunological Properties of Connective Tissue and Smooth Muscle Cells.- Immunologic Injury and Atherosclerosis.- Enzymic vs Non-Enzymic Factors in the Deterioration of Connective Tissue.- Calcification Processes in Atherosclerosis.