Bioactive Natural Products
Chemistry and Biology
(Sprache: Englisch)
Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising...
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Klappentext zu „Bioactive Natural Products “
Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes.The synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products are covered. It also features chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships. 40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biology.This book is aimed at natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.
Inhaltsverzeichnis zu „Bioactive Natural Products “
An OverviewUse of Chemical Genomics to Investigate the Mechanism of Action for Inhibitory Bioactive Natural CompoundsHigh-Throughput Drug Screening Based on Cancer Signaling in Natural Product ScreeningImmunosuppressants: Remarkable Microbial ProductsActivators and Inhibitors of ADAM-10 for Management of Cancer and Alzheimer's DiseaseStructure and Biological Activity of Polyether Ionophores and Their Semisynthetic DerivativesBioactive Flavaglines: Synthesis and PharmacologyBeneficial Effect of Naturally Occurring Antioxidants against Oxidative Stress-Mediated Organ DysfunctionsIsoquinoline Alkaloids and Their Analogs: Nucleic Acid and Protein Binding Aspects, and Therapeutic Potential for Drug DesignThe Potential of Peptides and Depsipeptides from Terrestrial and Marine Organisms in the Fight against Human Protozoan DiseasesSesquiterpene Lactones: A Versatile Class of Structurally Diverse Natural Products and Their Semisynthetic Analogs as Potential Anticancer AgentsNaturally Occurring Calanolides: Chemistry and BiologySelective Estrogen Receptor Modulators (SERMs) from PlantsIntroduction to the Biosynthesis and Biological Activities of PhenylpropanoidsNeuropeptides: Active Neuromodulators Involved in the Pathophysiology of Suicidal Behavior and Major Affective DisordersFrom Marine Organism to Potential Drug: Using Innovative Techniques to Identify and Characterize Novel Compounds - a Bottom-Up ApproachMarine Natural Products: Biodiscovery, Biodiversity, and Bioproduction
Autoren-Porträt
Having obtained his Ph.D. degree from Visva-Bharati University (India) in 1997, Dr. Goutam Brahmachari started his academic career in 1998 at the same University, where he is now a Full Professor of Organic Chemistry since 2011. At present, he is responsible for teaching courses in organic chemistry, green chemistry, natural products chemistry, and physical methods in organic chemistry. Several students have received their Ph.D. degree under the supervision of Professor Brahmachari during this period, and a dozen research fellows are presently working with him both in the fields of natural products and synthetic organic chemistry. He has authored and edited several books on organic synthesis and on the chemistry and pharmacology of natural products, and serves as a member of the Indian Association for the Cultivation of Science (IACS), Kolkata.
Bibliographische Angaben
- 2015, XXXIV, 508 Seiten, 30 farbige Abbildungen, 270 Schwarz-Weiß-Abbildungen, Maße: 17,9 x 25,2 cm, Gebunden, Englisch
- Herausgegeben: Goutam Brahmachari
- Verlag: Wiley-VCH
- ISBN-10: 3527337946
- ISBN-13: 9783527337941
- Erscheinungsdatum: 11.02.2015
Sprache:
Englisch
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