Cardiovascular Genomics: New Pathophysiological Concepts

1. Genomics and clinical cardiology: Hype or hope?.- Session 1: Gene expression analysis.- 2. Salt-sensitive hypertension: Identification of downstream renal targets in the aldosterone-signaling pathway by Serial Analysis of Gene Expression (SAGE).- 3. Cardiovascular proteomics: Effect of hypoxic conditions.- 4. Using comparative genome analysis to find interaction partners for frataxin.- Session 2: Genomics and pathophysiology of atherosclerosis.- 5. In vitro-in vivo gene expression analysis in atherosclerosis.- Session 3: Genomics in hypertension.- 6. Human essential hypertension: Role of the genes of the renin aldosterone system.- 7. Gene therapy for hypertension: Future or fiction?.- 8. Hormones and signalling pathways.- 9. Endothelial changes in hypertension.- Session 4: Genomics in cardiac hypertrophy and failure.- 10. Towards elucidation of genetic pathways in cardiac hypertrophy: Technique to develop microarrays.- 11. Gene expression in cardiac hypertrophy and failure: Role of G protein-coupled receptors.- 12. Little mice with big hearts: Finding the molecular basis for dilated cardiomyopathy.- 13. Cardiac hypertrophic signaling the good, the bad and the ugly.- Session 5: Molecular remodelling in arrhythmias.- 14. Ion channel regulation: From arrhythmias to genes to channels (to cures?).- 15. Differential expression and functional regulation of delayed rectifier channels.- 16. Genetic polymorphisms and their role in ventricular arrhythmias.- 17. Molecular mechanisms of remodeling in human atrial fibrillation.- 18. G-protein ß3-subunit polymorphism and atrial fibrillation.- Session 6: Towards cellular transplantion.- 19. Human stem cell gene therapy.- 20. Towards human embryonic stem cell derived cardiomyocytes.- 22. Cellular cardiac reinforcement.- 23. Appendixto session 3 hypertension Adducin paradigm: An approach to the complexity of hypertension genetics.