Cellular and Molecular Immunology

1. Properties and Overview of Immune Responses, 1

2. Cells and Tissues of the Immune System, 13

3. Leukocyte Circulation and Migration into Tissues, 35

4. Innate Immunity, 51

5. Antibodies and Antigens, 87

6. Major Histocompatibility Complex Molecules and Antigen Presentation to T Lymphocytes, 107

7. Immune Receptors and Signal Transduction, 137

8. Lymphocyte Development and Antigen Receptor Gene Rearrangement, 171

9. Activation of T Lymphocytes, 199

10. Differentiation and Functions of CD4+ Effector T Cells, 213

11. Differentiation and Functions of CD8+ Effector T Cells, 231

12. B Cell Activation and Antibody Production, 239

13. Effector Mechanisms of Humoral Immunity, 265

14. Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues, 289

15. Immunologic Tolerance and Autoimmunity, 315

16. Immunity to Microbes, 339

17. Transplantation Immunology, 359

18. Immunity to Tumors, 383

19. Hypersensitivity Disorders, 399

20. Allergy, 417

21. Congenital and Aquired Immunodeficiencies, 437

Appendix I. Glossary, 465

Appendix II. Cytokines, 493

Appendix III. Principle Features of Selected CD Molecules, 497

Appendix IV. Laboratory Techniques Commonly Used in Immunology, 503

Index, 517

Abul K. Abbas, MBBS, Distinguished Professor and Chair, Department of Pathology, University of California San Francisco, San Francisco, California