Central Neural Control of the Kidney
(Sprache: Englisch)
This study was undertaken to locate and characterisethe neurons in the central nervous system that project to thekidney. A retrograde transsynaptic viral tracer was injected into thekidney of rats and traced through the neuraxis to locate these neurons. The...
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This study was undertaken to locate and characterisethe neurons in the central nervous system that project to thekidney. A retrograde transsynaptic viral tracer was injected into thekidney of rats and traced through the neuraxis to locate these neurons. The results show that a polysynaptic neural pathway extends frommultiple forebrain sites including several novel autonomicsites, and projects successively through the brainstem, spinal cord andperipheral ganglia en route to the kidney. This pathway is activated inresponse to stimuli associated with the regulation of body fluidbalance. Both classical amino acid transmitters, and neuropeptideslikely mediate these effects. This work lays the foundation forpotential therapeutics in the treatment conditions of renal failure in whichthe central circuitry projecting to the renal nerves is compromised.
Autoren-Porträt von David Sly
Sly DavidDavid Sly, PE is a globally recognized expert in the design of Manufacturing Process Engineering and Factory Design tools and techniques. He received his BS, MS and PhD degrees in Industrial Engineering and an MBA from Iowa State University. David is president of Proplanner.COM, and an adjunct faculty member at Iowa State University.
Bibliographische Angaben
- Autor: David Sly
- 2008, 296 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: VDM Verlag Dr. Müller e.K.
- ISBN-10: 3639092082
- ISBN-13: 9783639092080
Sprache:
Englisch
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