Channels, Carriers, and Pumps
An Introduction to Membrane Transport
(Sprache: Englisch)
An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative...
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Klappentext zu „Channels, Carriers, and Pumps “
An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered.
Inhaltsverzeichnis zu „Channels, Carriers, and Pumps “
Chapters Structural Basis of Movement Across Cell Membranes Simple Diffusion of Nonelectrolytes and Ions Ion Channels Across Cell Membranes Carrier-Mediated Transport: Facilitated Diffusion Coupling of Flows of Substrates: Antiporters and Symporters Primary Active Transport Systems The Regulation and Integration of Transport Systems Appendices Single and Triple-Letter Codes for the Amino Acids Fundamental Constants, Conversion Factors, and Some Useful Approximations The Relation between the Permeability Coefficient Ps and the Half-Time t1/2 of Entry of a Permeant
Autoren-Porträt von Wilfred D. Stein, Thomas Litman
Wilfred Stein is the author of three previous books on membrane transport, the first appearing almost fifty years ago. He has edited numerous books and written some 180 papers on various aspects of membrane transport and especially transport kinetics. These papers, especially those written together with his colleague William Lieb, defined many of the concepts used today in discussing movement across cell membranes. More recently he has turned to the study of the kinetics of drugs used in cancer therapy and in the treatment of malaria. He has taught biochemistry, biophysics and physiology at the University of Manchester and the Hebrew University of Jerusalem and also at the Weizmann Institute in Israel. He is currently Emeritus Professor of Biophysics at the Hebrew University. He is married to a librarian and has four children and nine grandchildren.
Bibliographische Angaben
- Autoren: Wilfred D. Stein , Thomas Litman
- 2014, 2 Rev ed, 422 Seiten, Maße: 16,6 x 24,4 cm, Gebunden, Englisch
- Verlag: Academic Press
- ISBN-10: 0124165796
- ISBN-13: 9780124165793
- Erscheinungsdatum: 17.12.2014
Sprache:
Englisch
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