Computational Methods for Processing and Analysis of Biological Pathways
(Sprache: Englisch)
This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and...
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Klappentext zu „Computational Methods for Processing and Analysis of Biological Pathways “
This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways.Inhaltsverzeichnis zu „Computational Methods for Processing and Analysis of Biological Pathways “
Introduction.- Networks and Pathways in Systems Pharmacology.- Time Varying Methods for Pathway and Sub-Pathway Analysis.- Identification of Differentially Expressed Pathways and Sub-Pathways.
Autoren-Porträt von Anastasios Bezerianos, Andrei Dragomir, Panos Balomenos
Anastasios Bezerianos is a Professor at the Medical School of Patras University, Greece. He is also a Senior Principal Research Fellow at the Singapore Institute for Neurotechnology (SINAPSE) within the Centre for Life Sciences (CeLS), a Research Professor in the Department of Electrical and Computer Engineering (ECE), and a member of the Faculty of NUS Graduate School (NGS) for Integrative Sciences and Engineering at the National University of Singapore (NUS).Andrei Dragomir is a Research Assistant Professor at the Department of Biomedical Engineering of the University of Houston, TX, USA.
Panos Balomenos is a PhD Candidate at the Computer Engineering and Informatics Department of the University of Patras, Greece.
Bibliographische Angaben
- Autoren: Anastasios Bezerianos , Andrei Dragomir , Panos Balomenos
- 2017, 1st ed. 2017, VIII, 87 Seiten, 87 farbige Abbildungen, Maße: 15,6 x 24,1 cm, Kartoniert (TB), Englisch
- Verlag: Springer, Berlin
- ISBN-10: 3319538675
- ISBN-13: 9783319538679
- Erscheinungsdatum: 09.04.2017
Sprache:
Englisch
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