Coronaviruses and their Diseases

Structural Proteins.- Background Paper: Mapping Epitopes on Coronavirus Glycoproteins.- Binding of Antibodies that Strongly Neutralise Infectious Bronchitis Virus is Dependent on the Glycosylation of the Viral Peplomer Protein.- Enteric Coronavirus TGEV: Mapping of Four Major Antigenic Determinants in the Amino Half of Peplomer Protein E2.- Location of Antigenic Sites of the S-Glycoprotein of Transmissible Gastroenteritis Virus and their Conservation in Coronaviruses.- Topological and Functional Analysis of Epitopes on the S(E2) and HE(E3) Glycoproteins of Bovine Enteric Coronavirus.- Linear Neutralizing Epitopes on the Peplomer Protein of Coronaviruses.- The Nucleocapsid Protein of IBV Comprises Immunodominant Determinants Recognized by T-Cells.- 4: Expression and Immunogenicity of The Structural Proteins.- Background Paper: Progress Towards a Coronavirus Recombinant DNA Vaccine.- Protection of Mice from Lethal Coronavirus MHV-A59 Infection by Monoclonal Affinity-Purified Spike Glycoprotein.- Expression of the Spike Protein of Murine Coronavirus JHM Using a Baculovirus Vector.- Immunogenicity of Recombinant Feline Infectious Peritonitis Virus Spike Protein in Mice and Kittens.- Expression of TGEV Structural Genes in Virus Vectors.- 5: TBE Nucleocapsid (N) Protein.- Background Paper: Functions of the Coronavirus Nucleocapsid Protein.- Structure and Function Studies of the Nucleocapsid Protein of Mouse Hepatitis Virus.- MHV Leader RNA Secondary Structure Affects Binding to the Nucleocapsid Protein.- In Vivo and In Vitro Models of Demyelinating Disease: A Phosphoprotein Phosphatase in Host Cell Endosomes Dephosphorylating the Nucleocapsid Protein of Coronavirus JHM.- In Vivo and In Vitro Models of Demyelinating Disease: Possible Relationship Between Induction of Regulatory Subunit from cAMP Dependent Protein Kinase and Inhibition of JHMV Replication in Cultured Oligodendrocytes.- 6: The Polymerase and Other Non-Structural Proteins.- A Ribosomal Frameshift Signal in the Polymerase-Encoding Region of the IBV Genome.- Products of the Polymerase-Encoding Region of the Coronavirus IBV.- Murine Coronavirus Gene 1 Polyprotein Contains an Autoproteolytic Activity.- Detection of Mouse Hepatitis Virus Nonstructural Proteins Using Antisera Directed Against Bacterial Viral Fusion Proteins.- Nucleotide Sequence of the E2-Peplomer Protein Gene and Partial Nucleotide Sequence of the Upstream Polymerase Gene of Transmissible Gastroenteritis Virus (Miller Strain).- The Polymerase Gene of Corona- and Toroviruses: Evidence for an Evolutionary Relationship.- Characterization of the MHV-JHM Non-Structural Protein Encoded by mRNA 2.- 7: Transcription and Replication.- Background Paper: Transcription and Replication of Coronavirus RNA: a 1989 Update.- Coronavirus Subgenoraic Replicons as a Mechanism for mRNA Amplification.- Studies of Coronavirus DI RNA Replication Using In Vitro Constructed DI cDNA Clones.- Murine Coronavirus Temperature Sensitive Mutants.- Genomic Organisation of a Virulent Isolate of Porcine Transmissible Gastroenteritis Virus.- 8: Aspects of Coronavirus Variation and Evolufion.- Background Paper: Aspects of Coronavirus Evolution.- Molecular Basis of the Variation Exhibited by Avian Infectious Bronchitis Coronavirus (IBV).- Sequence Comparisons of the 3? End of the Genomes of Five Strains of Avian Infectious Bronchitis Virus.- Selection of Variants of Avian Infectious Bronchitis Virus Showing Tropism for Different Organs.- Monoclonal Antibody-Selected Variants of MHV-4 Contain Substitutions and Deletions in the E2 Spike Glycoprotein.- RNA Sequence Analysis of the E2 Genes of Wildtype and Neuroattenuated Mutants of MHV-4 Reveals a Hypervariable Domain.- Characterization of Attenuated Mutants of MHV3: Importance of the E2 Protein in Organ Tropism and Infection of Isolated Liver Cells.- Murine Hepatitis Virus JHM Variants Isolated from Wistar Furth Rats with Viral-Induced Neurological Disease.- 9: Porcine Respiratory Coronavirus.- Background Paper: The Appearance of the Porcine Respiratory Coronavirus has Created New Problems and Perspectives.- Induction of Milk IgA Antibodies by Porcine Respiratory Coronavirus Infection.- Sites of Replication of a Porcine Respiratory Coronavirus in 5-Week-01d Pigs with or Without Maternal Antibodies.- Infection with a New Porcine Respiratory Coronavirus in Denmark: Serologic Differentiation from Transmissible Gastroenteritis Virus Using Monoclonal Antibodies.- Molecular Aspects of the Relationship of Transmissible Gastroenteritis Virus (TGEV) with Porcine Respiratory Coronavirus (PRCV).- 10: Turkey and Bovine Coronaviruses.- Characterization and Location of the Structural Polypeptides of Turkey Enteric Coronavirus Using Monoclonal Antibodies and Enzymatic Treatments.- Evidence of Close Relatedness Between Turkey and Bovine Coronaviruses.- A Comparison of Bovine Coronavirus Strains Using Monoclonal Antibodies.- Analysis of Different Probe-Labeling Systems for Detection by Hybridization of Bovine Coronavirus.- 11: Non-Neurological Diseases.- Canine Coronavirus Infection in Cats; a Possible Role in Feline Infectious Peritonitis.- Characterization of an Attenuated Temperature Sensitive Feline Infectious Peritonitis Vaccine Virus.- Investigations into Resistance of Chicken Lines to Infection with Infectious Bronchitis Virus.- Comparison of the Replication of Distinct Strains of Human Coronavirus 0C43 in Organotypic Human Colon Cells(Caco-2) and Mouse Intestine.- Detection of Coronavirus RNA in CNS Tissue of Multiple Sclerosis and Control Patients.- Rabbit Dilated Cardiomyopathy.- Retinopathy Following Intravitreal Injection of Mice with MHV Strain JHM.- Reproductive Disorders in Female SHR Rats Infected with Sialodacryoadenitis Virus.- Mechanism of Protective Effect of Prostaglandin E in Murine Hepatitis Virus Strain 3 Infection: Effects on Macrophage Production of Tumour Necrosis Factor, Procoagulant Activity and Leukotriene B4.- Mouse Hepatitis Virus 3 Pathogenicity and B and T Lymphotropisms.- 12: Neurological Consequences of Murine Hepatitis Virus Infection of Mice.- Background Paper: Advances in the Study of MHV Infection of Mice.- T Cell-Mediated Clearance of JHMV from the Central Nervous System.- Immunopathogenesis of Demyelination Induced by MHV-4.- Localization of Virus and Antibody Response in Mice Infected Persistently with MHV-JHM.- Regulation of MHC Class I and II Antigens of Cerebral Endothelial Cells and Astrocytes Following MHV-4 Infection.- Mouse Hepatitis Virus A59 Increases Steady-State Levels of mRNAs Encoding Major Histocompatibility Complex Antigens.- Vacuolar Degeneration Induced by JHM-CC Virus in the CNS of Cyclophosphamide-Treated Mice.- Vacuolar Encephalomyelopathy in Mice Induced by Intracerebral Inoculation with a Coronavirus JHM-CC Strain.- Difference in Response of Susceptible Mouse Strains to a Small Plaque Mutant (JHM-CC) of Mouse Coronavirus.- 13: Neurological Consequences Of Murine Hepatitis Virus Infection of Rats.- Background Paper: On the Role of the Immune Response in the Course of Coronavirus JHM-Induced Encephalomyelitides in Mice and Rats.- Quantitation, Phenotypic Characterization and In Situ Localization of Lymphoid Cells in the Brain Parenchyma of Rats with Differing Susceptibility to Coronavirus JHM-Induced Encephalomyelitis.- Coronavirus Induced Demyelinating Encephalomyelitis in Rats: Immunopathological Aspects of Viral Persistency.- Astrocytes as Antigen Presenting Cells for Primary and Secondary T Cell Responses: Effect of Astrocyte Infection by Murine Hepatitis Virus.- Epigenetic Factors Influencing the Morphogenesis of Primary Neural Cell Cultures and the Concomitant Effects on Establishing JHMV Infections.