DNA

- Foreword

- Preface

- Acknowledgements

1. Biochemistry, Genetics, and Replication of DNA

1.1 Evolution of Identification: From Faces to Fingerprints to DNA

1.2 DNA and Heredity

1.3 DNA Replication

2. Biological Evidence--Science and Criminal Investigation

2.1 Crime Scene Investigation--Biological Evidence

2.2 Serology

2.3 Chain of Custody

3. Forensic DNA Analysis Methods

3.1 Associative Evidence and Polymorphism

3.2 Restriction Fragment-Length Polymorphism

3.3 Polymerase Chain Reaction

3.4 Analysis of Y-Chromosome STRS

3.5 Analysis of Mitochondrial DNA

3.6 Problems with PCR

3.7 Underlying Facts and Assumptions in Forensic DNA Testing

4. Genetics, Statistics, and Databases

4.1 Human Genetics, Population Genetics, and Statistics

4.2 Population Genetics

4.3 Need for Quality Control and Quality Assurance

4.4 SWGDAM (Formerly Known as TWGDAM) Standards

4.5 DNA Advisory Board

4.6 Mitochondrial DNA and Y-Chromosome STR Analysis and Statistical Calculations

4.7 Experimental Controls

4.8 Validation of New DNA Methods

4.9 Single-Nucleotide Polymorphism Analysis

4.10 Database Size and Composition

4.11 DNA Databases

4.12 Power of Discrimination

4.13 Mixtures and Statistics

4.14 Probability of Exclusion

4.15 Likelihood Ratio (LR)

4.16 Paternity Determinations

4.17 Lab Accreditation, Certification, Reputation, and Facilities

4.18 Reviewing a DNA Report--A Sample RFLP Analysis

4.19 Reviewing a DNA Report--A PCR-Based DNA Examination (HLADQA1, PM, D1S80, and CTT-CSF1PO, TPOX, THO1)

4.20 Reviewing a DNA Report--A PCR-STR-Based DNA Examination (CODIS Loci)

4.21 Reviewing a Paternity Report Based on Analysis of DNA

5. Litigating a DNA Case

5.1 Legal Theory

5.2 Admissibility of DNA Evidence

5.3 Legal Practice

5.4 DNA for Defense Attorneys--Contesting DNA Evidence

5.5 DNA for Prosecutors

5.6 DNA for Judges

6. DNA Evidence at Trial

6.1

LAWRENCE KOBILINSKY is currently the Associate Provost and a Professor of Biology and Immunology at John Jay College of Criminal Justice. An internationally renowned forensic scientist, he is a Fellow of the American Academy of Forensic Sciences as well as the New York Microscopical Society, and has published extensively in the areas of identification and individualization using protein genetic markers and DNA analysis.
 
THOMAS F. LIOTTI has represented clients in high-profile cases involving DNA. He is a Village Justice in Westbury, New York, and is currently a partner at the law offices of Thomas F. Liotti, located in Garden City, New York. He is a past president of the New York State Association of Criminal Defense Lawyers and Fellow in the American Board of Criminal Lawyers.
 
JAMEL OESER-SWEAT is a member of both the New York and New Jersey bars and has been admitted to practice before the Patent and Trademark Office. A former Westinghouse scholar, he has published several abstracts and articles in the field of microbiology, and has been a guest lecturer at several universities and conferences.

This valuable codebook will go a long way toward helping us win the 'DNA battle'...we owe the authors a great debt of gratitude." (New York Law Journal, December 15, 2004)

"There have been other forensic DNA books written before, but none has taken the reader through all aspects of DNA testing like this one...this book alone could make you feel prepared to understand a DNA case..." (Clinical Chemistry, September 2005)
 
"...a comprehensive, up-to-date discussion of forensic DNA technologies and their legal implications in the courtroom." (CHOICE, April 2005)
 
"...a concise guide to the use of DNA forensic analysis and how the information gained from such techniques are used in the legal system." (E-STREAMS, February 2005)
 
This valuable codebook will go a long way toward helping us win the 'DNA battle'...we owe the authors a great debt of gratitude." (New York Law Journal, December 15, 2004)