Epigenetics in Human Disease

Epigenetics of Human Disease

Methods and Strategies to Determine Epigenetic Variation in Human Disease

DNA Methylation Alterations in Human Cancers

Alterations of Histone Modifications in Cancer

MicroRNA in Oncogenesis

Epigenetic Approaches to Cancer Therapy

Epigenomics in Neurobehavioral Diseases

Emerging Role of Epigenetics in Human Neurodevelopmental Disorders

The Epigenetics of Alzheimer's Disease

Epigenetic Modulation of Human Neurobiological Disorders

Epigenetic Basis of Autoimmune Disorders in Humans

Approaches to Autoimmune Diseases Using Epigenetic Therapy

Epigenetic Mechanisms of Human Imprinting Disorders

Epigenomic Factors in Human Obesity

Epigenetic Approaches to Control Obesity

Epigenetics of Diabetes in Humans

The Potential of Epigenetic Compounds in Treating Diabetes

Epigenetic Aberrations in Human Allergic Diseases,

Therapy of Airway Disease: Epigenetic Potential

The Role of Epigenetics in Cardiovascular Disease

Epigenetics and Human Infectious Diseases

The Epigenetics of Endometriosis

Aberrant DNA Methylation in Endometrial Cancer

Stem Cell Epigenetics and Human Disease

Non-Coding RNA Regulatory Networks, Epigenetics, and Programming Stem Cell Renewal and Differentiation: Implications for Stem Cell Therapy

Aging and Disease: The Epigenetic Bridge

Early-Life Epigenetic Programming of Human Disease and Aging

Tollefsbol, Trygve
Professor of Biology, University of Alabama at Birmingham, Birmingham, AL. Dr. Tollefsbol is a Professor of Biology and a Senior Scientist in the Center for Aging, Comprehensive Cancer Center, Nutrition Obesity Research Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999 and a Steering Committee Member of the UAB Center for Aging. Dr. Tollefsbol trained as a Postdoctoral Fellow and Assistant Research Professor with members of the National Academy of Science at Duke University and the University of North Carolina. He earned doctorates in molecular biology and osteopathic medicine from the University of North Texas Health Sciences Center and his bachelor's degree in Biology from the University of Houston. He has received prior funding from the NIA, NCI, NHLBI, NIMH and other federal institutes as well as the Glenn Foundation for Medical Research, Susan G. Komen for the Cure, the American Federation for Aging Research (AFAR), and the American Institute for Cancer Research (AICR) among many other sources. The Glenn Foundation for Medical Research funding was unsolicited and was awarded to Dr. Tollefsbol for lifetime contributions to the field of aging. In 2006 Dr. Tollefsbol was selected and highlighted as part of the 25th anniversary of the AFAR for significant contributions to aging research. Dr. Tollefsbol's research interests have covered a wide range of topics such as aging, epigenetics, nutrition, cancer, telomerase, and caloric restriction. Work from his laboratory has been featured in Women's Health magazine, Shape magazine, and the AICR Newsletter and Dr. Tollefsbol has been a Scientist in the Spotlight in ScienceNow. Currently he serves as an Associate Editor for Frontiers in Epigenomics and is on the Editorial Boards of the international journals Open Longevity Science, Epigenetics of Diabetes and Obesity,

"This volume constitutes a comprehensive survey of the emerging field of epigenetics in the etiology, progression, diagnosis, prognosis and treatment of human diseases. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike."--Anticancer Research, Volume 33, Issue no. 5, May 2013 "This book covers a huge range of topics, from early life effects on adult disease to epigenetic changes occurring with aging and senescence. Especially pertinent are the several chapters on epigenetic treatments for disease including drugs, miRNA/siRNA, natural substances and foods. With up to date coverage of an ever expanding field, Epigenetics in Human Disease will be a great resource for clinicians, researchers and students."--Craig Cooney, Investigator, Research Service, Veteran's Affairs Medical Center, Little Rock, AR & Affiliate Scientist, Nanotechnology Center, University of Arkansas, Little Rock, AR

" This volume constitutes a comprehensive survey of the emerging field of epigenetics in the etiology, progression, diagnosis, prognosis and treatment of human diseases. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike." --Anticancer Research, Volume 33, Issue no. 5, May 2013 "This book covers a huge range of topics, from early life effects on adult disease to epigenetic changes occurring with aging and senescence. Especially pertinent are the several chapters on epigenetic treatments for disease including drugs, miRNA/siRNA, natural substances and foods. With up to date coverage of an ever expanding field, Epigenetics in Human Disease will be a great resource for clinicians, researchers and students."-- Craig Cooney, Investigator, Research Service, Veteran's Affairs Medical Center, Little Rock, AR & Affiliate Scientist, Nanotechnology Center, University of Arkansas, Little Rock, AR