Essential Concepts in Toxicogenomics
(Sprache: Englisch)
The field of toxicogenomics has been growing quickly, yet with rapid growth comes the need to periodically reflect on the nature of the field. Essential Concepts in Toxicogenomics collects reviews, opinion pieces and case studies from the leading experts in...
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The field of toxicogenomics has been growing quickly, yet with rapid growth comes the need to periodically reflect on the nature of the field. Essential Concepts in Toxicogenomics collects reviews, opinion pieces and case studies from the leading experts in this dynamic field with a focus on its application to pharmaceuticals. Topics covered include issues that affect the quality of toxicogenomics experiments, statistical approaches to their data analysis, the use of such data to build toxicogenomic models, and the utilization of genomics to identify biomarkers within the preclinical and clinical arenas. Although not in the standard Methods in Molecular Biology(TM) series format, this volume retains the practicality and usefulness of the highly successful series.
Informative and cutting-edge, Essential Concepts in Toxicogenomics is an ideal resource for pharmaceutical companies, chemical manufacturers, toxicologists, and all who must keep up-to-date on progress in this vital and important field.
Informative and cutting-edge, Essential Concepts in Toxicogenomics is an ideal resource for pharmaceutical companies, chemical manufacturers, toxicologists, and all who must keep up-to-date on progress in this vital and important field.
Klappentext zu „Essential Concepts in Toxicogenomics “
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Inhaltsverzeichnis zu „Essential Concepts in Toxicogenomics “
Toxicogenomics and Classical Toxicology: How to Improve Prediction and Mechanistic Understanding of Human ToxicityDonna L. Mendrick Use of Traditional Endpoints and Gene Dysregulation to Understand Mechanisms of Toxicity: Toxicogenomics in Mechanistic ToxicologyWayne R. Buck, Jeffrey F. Waring, Eric A. Blomme. Quality Control of Microarray Assays for Toxicogenomic and In Vitro Diagnostic Applications Karol L. Thompson and Joseph Hackett Role of Statistics in ToxicogenomicsMichael Elashoff Predictive Toxicogenomics in Preclinical DiscoveryScott A. Barros and Rory B. Martin In Vivo Predictive ToxicogenomicsMark W Porter Bioinformatics: Databasing and Gene AnnotationLyle D. Burgoon and Timothy R. Zacharewski Microarray Probe Mapping and Annotation in Cross-Species Comparative ToxicogenomicsJohn N Calley, William B Mattes, and Timothy Ryan Toxicogenomics in Biomarker DiscoveryMarc F. DeCristofaro and Kellye K. Daniels From Pharmacogenomics to Translational BiomarkersDonna L. Mendrick Public Consortium Efforts in ToxicogenomicsWilliam B. Mattes Applications of Toxicogenomics to Nonclinical Drug Development - Regulatory Science ConsiderationsFrank D. Sistare and Joseph J. DeGeorge
Bibliographische Angaben
- 2008, 300 Seiten, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: William B. Mattes, Donna L. Mendrick
- Verlag: Humana Press
- ISBN-10: 1588296385
- ISBN-13: 9781588296382
- Erscheinungsdatum: 30.05.2008
Sprache:
Englisch
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