Essential Developmental Biology
(Sprache: Englisch)
Essential Developmental Biology is a comprehensive, richly illustrated introduction to all aspects of developmental biology. Written in a clear and accessible style, the third edition of this popular textbook has been expanded and updatedIn addition, an...
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Klappentext zu „Essential Developmental Biology “
Essential Developmental Biology is a comprehensive, richly illustrated introduction to all aspects of developmental biology. Written in a clear and accessible style, the third edition of this popular textbook has been expanded and updatedIn addition, an accompanying website - www.essentialdevelopmentalbiology.com- provides instructional materials for both student and lecturer use, including animated developmental processes, a photo gallery of selected model organisms, and all artwork in downloadable format.With an emphasis throughout on the evidence underpinning the main conclusions, this book is an essential text for both introductory and more advanced courses in developmental biology.Reviews of the Second Edition: "The second edition is a must have for anyone interested in development biology. New findings in hot fields such as stem cells, regeneration, and aging should make it attractive to a wide readership. Overall, the book is concise, well structured, and illustrated. I can highly recommend it."--Peter Gruss, Max Planck Society"I have always found Jonathan Slack's writing thoughtful, provocative, and engaging, and simply fun to read. This effort is no exception. Every student of developmental biology should experience his holistic yet analytical view of the subject."--Margaret Saha, College of William & Mary
Inhaltsverzeichnis zu „Essential Developmental Biology “
Preface, ixAbout the companion website, xiiSection N: Groundwork, 1N The excitement of developmental biology, 3Where the subject came from, 3Impact of developmental biology, 4Future impact, 4Further reading, 5O How development works, 7Ultrashort summary, 7Gametogenesis, 10Early development, 12Morphogenetic processes, 19Growth and death, 23Further reading, 25P Approaches to development: developmental genetics, 27Developmental mutants, 27Sex chromosomes, 29Maternal and zygotic, 29Genetic pathways, 29Genetic mosaics, 32Screening for mutants, 33Cloning of genes, 34Gain- and loss-of-function experiments, 34Gene duplication, 38Limitations of developmental genetics, 39Further reading, 40Q Approaches to development: experimental embryology, 42Normal development, 42Developmental commitment, 45Criteria for proof, 51Further reading, 52R Approaches to development: cell and molecular biology techniques, 54Microscopy, 54Study of gene expression by molecular biology methods, 58Study of gene expression by in situ methods, 61Microinjection, 65Cell-labeling methods, 66Further reading, 68Section O: Major model organisms, 71S Model organisms, 73The big six, 73Access and micromanipulation, 75Genetics and genome maps, 75Relevance and tempo, 76Other organisms, 76Further reading, 78T Xenopus, 80Oogenesis, maturation, and fertilization, 80Normal development, 82Experimental methods, 87Processes of regional specification, 92Inductive interactions, 95Further reading, 104U The zebrafish, 106Normal development, 106Genetics, 110Embryological and molecular techniques, 114Regional specification, 115Other uses for the zebrafish, 118Further reading, 120V The chick, 121Normal development, 122Regional specifi cation of the early embryo, 127Description of organogenesis in the chick, 133Further reading, 140NM The mouse, 141Mammalian fertilization, 141Normal development, 145Regional specifi cation, 153Human early development, 158Mouse developmental genetics, 159Other topics in mouse development,
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164Further reading, 169NN Drosophila, 171Insects, 171Normal development, 173Drosophila developmental genetics, 178The developmental program, 181Further reading, 197NO Caenorhabditis elegans, 198Adult anatomy, 198Embryonic development, 200Analysis of postembryonic development, 208Further reading, 215Section 3: Organogenesis, 217NP Techniques for studying organogenesis and postnatal development, 219Genetics, 219Clonal analysis, 223Tissue and organ culture, 226Cell separation methods, 228Further reading, 230NQ Development of the nervous system, 231Overall structure and cell types, 231Anteroposterior patterning of the neural plate, 234Dorsoventral patterning of the neural tube, 238Neurogenesis and gliogenesis, 240The neural crest, 246Development of neuronal connectivity, 250Further reading, 257NR Development of mesodermal organs, 259Somitogenesis and myogenesis, 259The kidney, 266Germ cell and gonadal development, 269Limb development, 274Blood and blood vessels, 284The heart, 287Further reading, 293NS Development of endodermal organs, 296Normal development, 296Experimental analysis of endoderm development, 301The pancreas, 307Further reading, 312NT Drosophila imaginal discs, 314Metamorphosis, 314Disc development, 318Further reading, 328Section Q: Growth, regeneration, evolution, 331NU Tissue organization and stem cells, 333Types of tissue, 333Tissue renewal, 336Stem cells, 339Further reading, 360NV Growth, aging and cancer, 362Growth: control of size and proportion, 362Aging, 371Cancer, 374Further reading, 382OM Regeneration of missing parts, 384Distribution of regenerative capacity, 384Planarian regeneration, 385Insect limb regeneration, 388Vertebrate limb regeneration, 390General properties of regeneration, 399Further reading, 400ON Applications of pluripotent stem cells, 401Cell transplantation therapy, 401Embryonic stem cells, 403Personalized pluripotent stem cells, 406Proposed cell transplantation therapies using pluripotent stem cells, 411Further reading, 417OO Evolution and development, 419Macroevolution, 420The primordial animal, 424What really happened in evolution?, 429Further reading, 438Appendix: Key molecular components, 440Genes, 440Transcription factor families, 442Signaling systems, 443Inducing factor families, 445Cytoskeleton, 449Cell adhesion molecules, 451Extracellular matrix components, 452Further Reading, 452Glossary, 454Index, 467
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Autoren-Porträt von Jonathan M. W. Slack
PROFESSOR JONATHAN SLACK has worked in London, Oxford and Bath and is currently Director of the Stem Cell Institute at the University of Minnesota, USA. He is a member of the European Molecular Biology Organization and a Fellow of the Academy of Medical Sciences. He has published numerous research papers on developmental biology as well as three other books, of which the most recent is Stem Cells: A Very Short Introduction .Bibliographische Angaben
- Autor: Jonathan M. W. Slack
- 2012, 3. Aufl., 496 Seiten, Maße: 22,2 x 27,7 cm, Kartoniert (TB), Englisch
- Verlag: Wiley & Sons
- ISBN-10: 0470923512
- ISBN-13: 9780470923511
- Erscheinungsdatum: 16.11.2012
Sprache:
Englisch
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