Essentials of Apoptosis

Essentials of Apoptosis (2nd edition)

Table of Contents

Preface (2nd edition)

Preface (1st edition)

Contributors

Part I. Molecules and Pathways of Apoptosis

Chapter 1. Caspases: Activation, Regulation and Function
Stefan J. Riedl and Fiona L. Scott

Chapter 2. Bcl-2 Family Proteins
Wenxing Ding and Xiao-Ming Yin

Chapter 3. The Mammalian IAPs: Multi-faceted Inhibitors of Apoptosis
Eric C. LaCasse, Herman H. Cheung, Allison M. Hunter, Stephanie Plenchette, Douglas J. Mahoney and Robert G. Korneluk

Chapter 4. Structure Biology of Programmed Cell Death
Yigong Shi

Chapter 5. The Death Receptor Pathway
Maria Eugenia Guicciardi and Gregory J. Gores

Chapter 6. The Mitochondrial Pathway: Focus on Shape Changes
Silvia Campello and Luca Scorrano

Chapter 7. The Endoplasm Reticulum Pathway
Michael W. Harr and Clark W. Distelhorst

Chapter 8. Reactive Oxygen Species in Cell Fate Decisions
Han-Ming Shen and Shazib Pervaiz

Chapter 9. The Integration of Metabolism and Cell Death
Jonathan L. Coloff, Yuxing Zhao and Jeffrey C. Rathmell

Chapter 10. Transcriptional Regulation of Apoptosis
Crissy Dudgeon, Wei Qiu, Quanhong Sun, Lin Zhang and Jian Yu

Chapter 11. Clearance of Apoptotic cells --Mechanisms and Consequences
Carylin J. Marek and Lars-Peter Erwig

Chapter 12. Systems Biology Approach to the Study of Apoptosis
Heinrich Huber, Eric Bullinger and Markus Rehm

Part II: Apoptosis in Model Organisms

Chapter 13. Programmed Cell Death in Plants: Apoptotic but not Quite
Naohide Watanabe and Eric Lam

Chapter 14. Tracing the Roots of Death: Apoptosis in Saccharomyces cerevisiae
Didac Carmona-Gutierrez and Frank Madeo

Chapter 15. Programmed Cell Death in C. elegans.
Monica Darland-Ransom, Yi-Chun Wu and Ding Xue

Chapter 16. Cell Death in Drosophila.
Dianne C. Purves, Jessica P. Monserrate and Carrie Baker Brachmann

Part III. Apoptosis in Mammalian Physiology and Pathogenesis

Chapter 17. Cell Death: Defining

From the reviews of the second edition:

"This book comprehensively reviews knowledge of the main mechanism of cell death, apoptosis, both from the molecular viewpoint and in relation to the roles of this process in mammalian physiology and pathology. ... chapters are well written and scholarly in content and present the reader with a thorough and up-to-date insight into these fields. This book is highly recommended for scientists working in many areas of cell or developmental biology, as well as those involved in more clinical fields, such as neurobiology or molecular oncology." (Mike Clemens, Microbiology Today, November, 2009)

"The book 'Essentials of Apoptosis' is a collection of 31 review articles, covering a wide variety of approaches in studying cell death. ... It enables the reader to get acquainted with many aspects of apoptosis, and impressive amounts of references cited in each of the article allows for further studies on the subject. I recommend this book to anyone seriously interested in research on programmed dell death." (Piotr P. Stepien, Acta Biochimica Polonica, December, 2010)

"Prof. Yin and Prof. Dong ... were able to cover both conceptual and practical aspects as well as both basic and applied research aspects, thus leading to translation research aspects in biomedicine, which is a crucial hot topic in modern biomedical clinic. ... the potential readership is made up of the entire scientific comunity ... and cellular biologists, developmental biologists, protein scientists." (CarloAlberto Redi, European Journal of Histochemistry, Vol. 54 (e11), 2010)

"Comprehensive overview of the history and current knowledge of the study of the genetic program of cell death ... . the book is to inform the basic researcher and the clinician interested in understanding how inappropriate apoptosis may underlie their area of scientific interest, and in this respect it succeeds. ... a welcome addition for the collection of a